Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1071334..1071785 Replicon chromosome
Accession NZ_CP076249
Organism Xanthomonas translucens pv. hordei strain UPB458

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag KFS86_RS04915 Protein ID WP_230939940.1
Coordinates 1071334..1071483 (+) Length 50 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag KFS86_RS04920 Protein ID WP_196480047.1
Coordinates 1071603..1071785 (+) Length 61 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFS86_RS04870 (KFS86_04845) 1066448..1067116 + 669 WP_003479795.1 dTMP kinase -
KFS86_RS04875 (KFS86_04850) 1067113..1068090 + 978 WP_003479796.1 DNA polymerase III subunit delta' -
KFS86_RS04880 (KFS86_04855) 1068087..1068440 + 354 WP_003479797.1 PilZ domain-containing protein -
KFS86_RS04890 (KFS86_04865) 1068731..1068988 - 258 WP_058195736.1 Txe/YoeB family addiction module toxin -
KFS86_RS04895 (KFS86_04870) 1068985..1069236 - 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
KFS86_RS04900 (KFS86_04875) 1069345..1069878 + 534 Protein_953 endonuclease -
KFS86_RS04905 (KFS86_04880) 1069875..1070597 - 723 WP_058360631.1 helix-turn-helix transcriptional regulator -
KFS86_RS04910 (KFS86_04885) 1070721..1071164 + 444 WP_058360632.1 nuclear transport factor 2 family protein -
KFS86_RS04915 1071334..1071483 + 150 WP_230939940.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KFS86_RS04920 (KFS86_04895) 1071603..1071785 + 183 WP_196480047.1 hypothetical protein Antitoxin
KFS86_RS20235 1072624..1072755 + 132 WP_269113130.1 hypothetical protein -
KFS86_RS04930 (KFS86_04905) 1072911..1075361 - 2451 WP_081049173.1 DEAD/DEAH box helicase family protein -
KFS86_RS04935 (KFS86_04910) 1075348..1075902 - 555 WP_058360994.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 50 a.a.        Molecular weight: 5326.12 Da        Isoelectric Point: 8.5858

>T204992 WP_230939940.1 NZ_CP076249:1071334-1071483 [Xanthomonas translucens pv. hordei]
MDDETYAKLQVLLQENLEVGDLIEGTGGLRKVRVAAKGHGKRGGARVIY

Download         Length: 150 bp

>T204992 NZ_CP101310:3053806-3054093 [Escherichia coli]
ATGTTACCCGTGTTATGGCTTGAAAGCGCAGATACCGACCTAGATGATATAACTAGTTATATTGCTCGTTTCGACATAGA
TGCGGCAGAACGCTTATGGCAGCGATTAAGGGGGTGTGTGCTGCCGTTATCCGAACACCCGTATTTATACCCACCAAGCG
ACAGAGTACCTGGCTTGCGTGAGATTGTAGCTCACCCTAACTATATAATTCTTTACCGTGTAGCCACTTTAAGCATTGAG
ATCGTGAGTGTAGTACACGCCAGACGCCAATTCCCCAAGCAGAACTAA

Antitoxin


Download         Length: 61 a.a.        Molecular weight: 6745.77 Da        Isoelectric Point: 8.9195

>AT204992 WP_196480047.1 NZ_CP076249:1071603-1071785 [Xanthomonas translucens pv. hordei]
MSKFFEALMESVQQMDEIVRGERAPSREFHVDAIQVKQVRLPASPSLRAANKTMEVAAGR

Download         Length: 183 bp

>AT204992 NZ_CP101310:3053614-3053802 [Escherichia coli]
ATGAATACGGCCCTTTCACCAATGGTTTCTGAGTTCGAAACCATTGAACAAGAAAACAGTTACAACGAATGGCTGCGTGC
GAAAGTAGCAGCGAGCCTTGCAAATCCGCGCCCAGCAATTCCCCATGACGAGGTTGAGCGCAGAATGGCAGAACGCTTTG
CTAAAATGCGCAAGGAACGGAGTAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References