Detailed information of TA system TA204987

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): higBA (relBE)/-
• Location: 1071298..1071749
• Replicon: chromosome
• Accession: NZ_CP076248
• Organism: Xanthomonas translucens pv. hordei strain UPB947

Toxin (Protein)

• Gene name: higB
• Uniprot ID: -
• Locus tag: KFS83_RS04915
• Protein ID: WP_230939940.1
• Coordinates: 1071298..1071447 (+)
• Length: 50 a.a.

Antitoxin (Protein)

• Gene name: higA
• Uniprot ID: -
• Locus tag: KFS83_RS04920
• Protein ID: WP_196480047.1
• Coordinates: 1071567..1071749 (+)
• Length: 61 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KFS83_RS04870 (KFS83_04845)	1066412..1067080	+	669	WP_003479795.1	dTMP kinase	-
KFS83_RS04875 (KFS83_04850)	1067077..1068054	+	978	WP_003479796.1	DNA polymerase III subunit delta'	-
KFS83_RS04880 (KFS83_04855)	1068051..1068404	+	354	WP_003479797.1	PilZ domain-containing protein	-
KFS83_RS04890 (KFS83_04865)	1068695..1068952	-	258	WP_058195736.1	Txe/YoeB family addiction module toxin	-
KFS83_RS04895 (KFS83_04870)	1068949..1069200	-	252	WP_003468816.1	type II toxin-antitoxin system prevent-host-death family antitoxin	-
KFS83_RS04900 (KFS83_04875)	1069309..1069842	+	534	Protein_954	endonuclease	-
KFS83_RS04905 (KFS83_04880)	1069839..1070561	-	723	WP_058360631.1	helix-turn-helix transcriptional regulator	-
KFS83_RS04910 (KFS83_04885)	1070685..1071128	+	444	WP_058360632.1	nuclear transport factor 2 family protein	-
KFS83_RS04915	1071298..1071447	+	150	WP_230939940.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
KFS83_RS04920 (KFS83_04895)	1071567..1071749	+	183	WP_196480047.1	hypothetical protein	Antitoxin
KFS83_RS04930	1072588..1072719	+	132	WP_269113130.1	hypothetical protein	-
KFS83_RS04935 (KFS83_04905)	1072875..1075325	-	2451	WP_081049173.1	DEAD/DEAH box helicase family protein	-
KFS83_RS04940 (KFS83_04910)	1075312..1075866	-	555	WP_058360994.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-73)

Sequences

Toxin

Protein

• Length: 50 a.a.
• Molecular weight: 5326.12 Da
• Isoelectric Point: 8.5858

>T204987 WP_230939940.1 NZ_CP076248:1071298-1071447 [Xanthomonas translucens pv. hordei]
MDDETYAKLQVLLQENLEVGDLIEGTGGLRKVRVAAKGHGKRGGARVIY

Nucleotide

• Length: 150 bp

>T204987 NZ_CP101310:1866916-1867170 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACACCATTTGAAGGTAAGGGGAAACCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACTGATGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin

Protein

• Length: 61 a.a.
• Molecular weight: 6745.77 Da
• Isoelectric Point: 8.9195

>AT204987 WP_196480047.1 NZ_CP076248:1071567-1071749 [Xanthomonas translucens pv. hordei]
MSKFFEALMESVQQMDEIVRGERAPSREFHVDAIQVKQVRLPASPSLRAANKTMEVAAGR

Nucleotide

• Length: 183 bp

>AT204987 NZ_CP101310:1866668-1866919 [Escherichia coli]
ATGCGTACAATTAGTTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA