Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | ldrD-sokW/Ldr(toxin) |
| Location | 277099..277320 | Replicon | chromosome |
| Accession | NZ_CP076235 | ||
| Organism | Escherichia coli O157:H7 strain 9.1_Anguil | ||
Toxin (Protein)
| Gene name | ldrD | Uniprot ID | S1NWX0 |
| Locus tag | JKN68_RS01345 | Protein ID | WP_001295224.1 |
| Coordinates | 277213..277320 (+) | Length | 36 a.a. |
Antitoxin (RNA)
| Gene name | sokW | ||
| Locus tag | - | ||
| Coordinates | 277099..277164 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JKN68_RS01325 (272539) | 272539..273441 | + | 903 | WP_000084677.1 | dipeptide ABC transporter permease DppC | - |
| JKN68_RS01330 (273452) | 273452..274435 | + | 984 | WP_001196486.1 | dipeptide ABC transporter ATP-binding protein | - |
| JKN68_RS01335 (274432) | 274432..275436 | + | 1005 | WP_000107027.1 | dipeptide ABC transporter ATP-binding subunit DppF | - |
| JKN68_RS01340 (275466) | 275466..276737 | - | 1272 | WP_001301684.1 | aromatic amino acid transport family protein | - |
| - (277099) | 277099..277164 | - | 66 | NuclAT_16 | - | Antitoxin |
| - (277099) | 277099..277164 | - | 66 | NuclAT_16 | - | Antitoxin |
| - (277099) | 277099..277164 | - | 66 | NuclAT_16 | - | Antitoxin |
| - (277099) | 277099..277164 | - | 66 | NuclAT_16 | - | Antitoxin |
| - (277099) | 277099..277164 | - | 66 | NuclAT_21 | - | Antitoxin |
| - (277099) | 277099..277164 | - | 66 | NuclAT_21 | - | Antitoxin |
| - (277099) | 277099..277164 | - | 66 | NuclAT_21 | - | Antitoxin |
| - (277099) | 277099..277164 | - | 66 | NuclAT_21 | - | Antitoxin |
| JKN68_RS01345 (277213) | 277213..277320 | + | 108 | WP_001295224.1 | type I toxin-antitoxin system toxin Ldr family protein | Toxin |
| JKN68_RS01350 (277407) | 277407..279086 | - | 1680 | WP_000191596.1 | cellulose biosynthesis protein BcsG | - |
| JKN68_RS01355 (279083) | 279083..279274 | - | 192 | WP_000988308.1 | cellulose biosynthesis protein BcsF | - |
| JKN68_RS01360 (279271) | 279271..280842 | - | 1572 | WP_001204920.1 | cellulose biosynthesis c-di-GMP-binding protein BcsE | - |
| JKN68_RS01365 (281115) | 281115..281303 | + | 189 | WP_001063316.1 | cellulose biosynthesis protein BcsR | - |
| JKN68_RS01370 (281315) | 281315..282067 | + | 753 | Protein_272 | cellulose biosynthesis protein BcsQ | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 3882.70 Da Isoelectric Point: 9.0157
>T204829 WP_001295224.1 NZ_CP076235:277213-277320 [Escherichia coli O157:H7]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK
Download Length: 108 bp
>T204829 NZ_CP101263:1835434-1835688 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAACTTATCAAAGATACCCGCAGAACGCCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GTTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA
Antitoxin
Download Length: 66 bp
>AT204829 NZ_CP076235:c277164-277099 [Escherichia coli O157:H7]
GTCTAGGTTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT
GTCTAGGTTCAAGATTAGCCCCCGTGGTGTTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
