Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) ldrD-rdlD/Ldr(toxin)
Location 3924811..3925033 Replicon chromosome
Accession NZ_CP076123
Organism Escherichia coli strain F11

Toxin (Protein)


Gene name ldrD Uniprot ID S1NWX0
Locus tag F11EC_RS18785 Protein ID WP_001295224.1
Coordinates 3924811..3924918 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name rdlD
Locus tag -
Coordinates 3924967..3925033 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
F11EC_RS18760 3920064..3920816 - 753 WP_000279536.1 cellulose biosynthesis protein BcsQ -
F11EC_RS18765 3920828..3921016 - 189 WP_001063314.1 cellulose biosynthesis protein BcsR -
F11EC_RS18770 3921289..3922860 + 1572 WP_001204945.1 cellulose biosynthesis c-di-GMP-binding protein BcsE -
F11EC_RS18775 3922857..3923048 + 192 WP_000988308.1 cellulose biosynthesis protein BcsF -
F11EC_RS18780 3923045..3924724 + 1680 WP_000191565.1 cellulose biosynthesis protein BcsG -
F11EC_RS18785 3924811..3924918 - 108 WP_001295224.1 type I toxin-antitoxin system toxin Ldr family protein Toxin
- 3924967..3925033 + 67 - - Antitoxin
F11EC_RS18790 3925394..3926665 + 1272 WP_001298005.1 aromatic amino acid transport family protein -
F11EC_RS18795 3926695..3927699 - 1005 WP_000103577.1 dipeptide ABC transporter ATP-binding subunit DppF -
F11EC_RS18800 3927696..3928679 - 984 WP_001196477.1 dipeptide ABC transporter ATP-binding protein -
F11EC_RS18805 3928690..3929592 - 903 WP_000084677.1 dipeptide ABC transporter permease DppC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Type I toxin-antitoxin system, toxin Ldr

(1-35)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 3882.70 Da        Isoelectric Point: 9.0157

>T204676 WP_001295224.1 NZ_CP076123:c3924918-3924811 [Escherichia coli]
MTLAELGMAFWHDLAAPVIAGILASMIVNWLNKRK

Download         Length: 108 bp

>T204676 NZ_CP101210:1977518-1977769 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTTATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGCTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACAGAAAAGGAC
ATTATTGAGTGA

Antitoxin


Download         Length: 67 bp

>AT204676 NZ_CP076123:3924967-3925033 [Escherichia coli]
GTCTAGGTTCAAGATTAGCCCCCGTGATATTGTCAGGTGCATACCTGCAACGTGCGGGGGTTTTCTC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4P7TSJ7

Antitoxin

Download structure file

References