Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprA1-sprA1AS/-
Location 1794886..1795068 Replicon chromosome
Accession NZ_CP076105
Organism Staphylococcus aureus subsp. aureus RN4220

Toxin (Protein)


Gene name sprA1 Uniprot ID -
Locus tag KMZ21_RS08590 Protein ID WP_001801861.1
Coordinates 1794886..1794981 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1795009..1795068 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KMZ21_RS08550 (KMZ21_08550) 1790546..1791172 + 627 WP_000669046.1 hypothetical protein -
KMZ21_RS08555 (KMZ21_08555) 1791213..1791557 + 345 WP_000627551.1 DUF3969 family protein -
KMZ21_RS08560 (KMZ21_08560) 1791655..1792206 + 552 WP_000414205.1 hypothetical protein -
KMZ21_RS08565 (KMZ21_08565) 1792424..1793065 - 642 WP_000494956.1 ImmA/IrrE family metallo-endopeptidase -
KMZ21_RS08570 (KMZ21_08570) 1793179..1793364 - 186 WP_000809857.1 hypothetical protein -
KMZ21_RS08575 (KMZ21_08575) 1793366..1793542 - 177 WP_000375476.1 hypothetical protein -
KMZ21_RS08580 (KMZ21_08580) 1793553..1793936 - 384 WP_000070812.1 hypothetical protein -
KMZ21_RS08585 (KMZ21_08585) 1794540..1794683 - 144 WP_001549059.1 transposase -
KMZ21_RS08590 (KMZ21_08590) 1794886..1794981 + 96 WP_001801861.1 type I toxin-antitoxin system Fst family toxin PepA1 Toxin
- 1795009..1795068 - 60 - - Antitoxin
KMZ21_RS08595 (KMZ21_08595) 1795104..1795205 + 102 WP_001791893.1 hypothetical protein -
KMZ21_RS08600 (KMZ21_08600) 1795183..1795359 - 177 Protein_1690 transposase -
KMZ21_RS08605 (KMZ21_08605) 1795553..1795930 - 378 WP_001037045.1 DUF1433 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3554.32 Da        Isoelectric Point: 10.4449

>T204628 WP_001801861.1 NZ_CP076105:1794886-1794981 [Staphylococcus aureus subsp. aureus RN4220]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Download         Length: 96 bp

>T204628 NZ_CP101176:c4594415-4594281 [Xanthomonas campestris pv. campestris]
ATGAAGCGTGCAATTGCATTGTTGGTGCTGTCGATGTTGTCGGTGGGAATGCTGGCGGGTTGCAACACCGTCGCAGGTGC
CGGCAAGGACGTGCAGGGCGCTGGCGAGAAGGTGGAAGACGCCGCGCGCAAGTGA

Antitoxin


Download         Length: 60 bp

>AT204628 NZ_CP076105:c1795068-1795009 [Staphylococcus aureus subsp. aureus RN4220]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References