Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2701763..2702262 Replicon chromosome
Accession NZ_CP076104
Organism Nocardioides sp. LMS-CY

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag KM427_RS13050 Protein ID WP_215524138.1
Coordinates 2701763..2702020 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag KM427_RS13055 Protein ID WP_215524139.1
Coordinates 2702017..2702262 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KM427_RS13020 (KM427_13020) 2697949..2698497 + 549 WP_215527462.1 GNAT family protein -
KM427_RS13025 (KM427_13025) 2698519..2699082 - 564 WP_183594744.1 dihydrofolate reductase family protein -
KM427_RS13030 (KM427_13030) 2699147..2699716 - 570 WP_215527463.1 dienelactone hydrolase family protein -
KM427_RS13035 (KM427_13035) 2699784..2700377 + 594 WP_252274451.1 winged helix-turn-helix domain-containing protein -
KM427_RS13040 (KM427_13040) 2700311..2700844 - 534 WP_215524136.1 sigma-70 family RNA polymerase sigma factor -
KM427_RS13045 (KM427_13045) 2700846..2701676 - 831 WP_215524137.1 hypothetical protein -
KM427_RS13050 (KM427_13050) 2701763..2702020 - 258 WP_215524138.1 Txe/YoeB family addiction module toxin Toxin
KM427_RS13055 (KM427_13055) 2702017..2702262 - 246 WP_215524139.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
KM427_RS13060 (KM427_13060) 2702579..2703052 + 474 WP_215524140.1 hypothetical protein -
KM427_RS13065 (KM427_13065) 2703099..2703494 + 396 WP_215524141.1 MmcQ/YjbR family DNA-binding protein -
KM427_RS13070 (KM427_13070) 2703507..2705867 - 2361 WP_215524142.1 excinuclease ABC subunit UvrA -
KM427_RS13075 (KM427_13075) 2705967..2706194 - 228 WP_221200110.1 hypothetical protein -
KM427_RS13080 (KM427_13080) 2706206..2706619 - 414 WP_183594737.1 VOC family protein -
KM427_RS13085 (KM427_13085) 2706630..2707088 - 459 WP_215524143.1 helix-turn-helix transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-71)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10124.53 Da        Isoelectric Point: 7.4014

>T204624 WP_215524138.1 NZ_CP076104:c2702020-2701763 [Nocardioides sp. LMS-CY]
VRLVFTPNGWDDYQHWLQADRQILKRINRLIDDALRDPTDGIGKPEPLRHMFAGAWSRRITDEHRLVYLVDGEDLVVLQA
RFHYK

Download         Length: 258 bp

>T204624 NZ_CP101174:3696501-3696992 [Xanthomonas campestris pv. campestris]
ATGACGGTATCGGCGCCGGAACCGCTGACAGCGCATCACCGGGTCGAACCGTTCGCATCGGGCGTGGAGAGCCTGGATCA
CTGGCTCAAGCGCCGCGCCCTGAAAAATCAGGCAACCGGTGCGTCACGGACCTTCGTTGCCTGCGAGGATGACCGCGTGG
TGGCCTATTACGCCCTGGCGTCGAGTGCGGTCGCCGTGGACGCGACGCCCGGCCGCTTCCGTCGCAACATGCCGGACCCG
ATCCCCGTGGTGGTGCTTGGGAGGCTTGCTGTTGACCAATCCCTGCATGGCAGAGGTTTTGGCCGCGCCCTGATGCAGGA
TGCTGGCAAGCGCATCTTGCATGCGGCCGACACCATCGGCATTCGCGGGCTGCTCGTGCATGCGCTCTCGGCGGACGCCA
AGGCGTTTTACGAGCGCATCGGCTTCGAACCTTCCCCGCTGGATCCCATGGTGCTGGTCGTCACGCTGGAAGACCTGAAA
GCCAGTCTGTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9083.30 Da        Isoelectric Point: 5.7152

>AT204624 WP_215524139.1 NZ_CP076104:c2702262-2702017 [Nocardioides sp. LMS-CY]
MPVTASEARKQLFPLIEKVNNDRIAVEITSRRGNAVLISAEEFAALEETAYLLRVPANAKRLLESLQQARSGDRHEHELA
E

Download         Length: 246 bp

>AT204624 NZ_CP101174:3696214-3696504 [Xanthomonas campestris pv. campestris]
ATGTCCACACCCAACACTACGCCTGGCAAGCGCGAAACCTTGAATCTCCGCATCAAGCCGGAGGAGCGCAGCCTGATCGA
CCGGGCCGCCAAGGCGCGCGGGAAGAACCGCACCGATTTCATGCTGGACGCAGCGCGCTCGGCGGCCGAGGAAGCCTTGC
TGGACCAGACCCTCATCACGGCCAGCCCGGACGCCTACGCCGCCTTTTTGGCACGGCTGGACATGCCGCCGCAGCCGAAC
GCGCGCCTGCGCAAGACGATGCAGACGCCCGCTCCTTGGGAGAAGGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References