Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 1963160..1963683 Replicon chromosome
Accession NZ_CP076029
Organism Staphylococcus sp. MZ9

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag KI244_RS09850 Protein ID WP_045177693.1
Coordinates 1963160..1963426 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID T1YBB2
Locus tag KI244_RS09855 Protein ID WP_000587618.1
Coordinates 1963426..1963683 (-) Length 86 a.a.

Genomic Context

KI244_RS09860KI244_RS09870KI244_RS09830KI244_RS09835KI244_RS09840KI244_RS09845KI244_RS09850KI244_RS09855KI244_RS09865
Location: 1964043..1964498 (456 bp)
Type: Others
Protein ID: WP_000732090.1
Location: 1966438..1967187 (750 bp)
Type: Others
Protein ID: WP_000072443.1
Location: 1958466..1959653 (1188 bp)
Type: Others
Protein ID: WP_045177690.1
Location: 1960049..1960825 (777 bp)
Type: Others
Protein ID: WP_000072151.1
Location: 1960818..1961480 (663 bp)
Type: Others
Protein ID: WP_045177691.1
Location: 1961728..1962804 (1077 bp)
Type: Others
Protein ID: WP_001076673.1
Location: 1963160..1963426 (267 bp)
Type: Toxin
Protein ID: WP_045177693.1
Location: 1963426..1963683 (258 bp)
Type: Antitoxin
Protein ID: WP_000587618.1
Location: 1964666..1966243 (1578 bp)
Type: Others
Protein ID: WP_000143503.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
KI244_RS09830 (KI244_09830)1958466..1959653-1188WP_045177690.1MFS transporter-
KI244_RS09835 (KI244_09835)1960049..1960825-777WP_000072151.1iron export ABC transporter permease subunit FetB-
KI244_RS09840 (KI244_09840)1960818..1961480-663WP_045177691.1ATP-binding cassette domain-containing protein-
KI244_RS09845 (KI244_09845)1961728..1962804-1077WP_001076673.1M42 family metallopeptidase-
KI244_RS09850 (KI244_09850)1963160..1963426-267WP_045177693.1Txe/YoeB family addiction module toxinToxin
KI244_RS09855 (KI244_09855)1963426..1963683-258WP_000587618.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
KI244_RS09860 (KI244_09860)1964043..1964498+456WP_000732090.1YehR family lipoprotein-
KI244_RS09865 (KI244_09865)1964666..1966243-1578WP_000143503.1FMN-binding glutamate synthase family protein-
KI244_RS09870 (KI244_09870)1966438..1967187+750WP_000072443.1CPBP family lipoprotein N-acylation protein LnsB-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(26-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10684.35 Da        Isoelectric Point: 10.1384

>T204577 WP_045177693.1 NZ_CP076029:c1963426-1963160 [Staphylococcus sp. MZ9]
MSNYTVKIKNSAKLDLKKIKHPYLKKSFLEIVETLKNDPYKITQSFEKLEPKYLERYSRRINHQHRVVYTVDDRNKEVLI
LSAWSHYD

Download         Length: 267 bp

>T204577 NZ_CP101115:487285-487680 [Acinetobacter sp. Z1]
ATGTCCATGGCTAGTCGTCTTTTCGAGCTGCAATACAGCCGTTTTTCGATTGTATTGCAGCTTTTTGTATTTCTTACTAT
TTCAATTCTAAGCTATCAATTACTCCATATGATGTTGTGGTTGTTAAGTCTCGGAATCATGGCTTTCGCATGGTTTAAGC
TATCCAAGCAGCCATCCATCATTCGTTTTGAATATTTAGATCAACACATCTGGTCGTTTGAATTTTCAGATAAGAATTTA
GCAATTCAACGTTTGAAGATTACTAAAATAATTGACCATAAAGCTTATGTTTCAATTCATATTGCTGACTCGAGTTGCAA
AACTTACATCATTTGGTGGGATCAATTGTCATATTTGCAATGGAAAAATCTAAAATTACTGGCAAAACTGATTTGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9762.78 Da        Isoelectric Point: 4.1958

>AT204577 WP_000587618.1 NZ_CP076029:c1963683-1963426 [Staphylococcus sp. MZ9]
MIITSPTEARKDFYQLLKNVNNNHEPIYISGNNAENNAVIIGLEDWKSIQETMYLVSTGTMDKVREREKDNSGTTNIDDI
DWDNL

Download         Length: 258 bp

>AT204577 NZ_CP101115:487041-487298 [Acinetobacter sp. Z1]
ATGTCTGATGAAATGACTCTTGAAGAACGTAAAGTAATTTATCGCGCACGTCGTGGTTTAAAAGAAATTGATGTGTATTT
TGATCCTTATGTGAAGAATCACTATTTAACCGCTGATCAAGCAGAAAAAGCTTTGTTTGCTGAATTGGTTGAGCAAGAAG
ATCCTGATTTGCTTGATTGGTTTATGGAAGTCGGTGAACCACCGCGAAATGAATTAAAAGATTTTATTTTAAAACTAAAA
CATTATGTCCATGGCTAG

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
AlphaFold DBT1YBB2

References