Detailed information of TA system TA204575

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 1931960..1932144
• Replicon: chromosome
• Accession: NZ_CP076029
• Organism: Staphylococcus sp. MZ9

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: KI244_RS09710
• Protein ID: WP_000482647.1
• Coordinates: 1932037..1932144 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	1931960..1932020 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KI244_RS09695 (KI244_09695)	1927411..1927578	-	168	WP_001790576.1	hypothetical protein	-
KI244_RS09700 (KI244_09700)	1927809..1929542	-	1734	WP_000486494.1	ABC transporter ATP-binding protein	-
KI244_RS09705 (KI244_09705)	1929567..1931330	-	1764	WP_006191000.1	ABC transporter ATP-binding protein	-
-	1931960..1932020	+	61	-	-	Antitoxin
KI244_RS09710 (KI244_09710)	1932037..1932144	-	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
KI244_RS09715 (KI244_09715)	1932278..1932664	-	387	WP_000779360.1	flippase GtxA	-
KI244_RS09720 (KI244_09720)	1932932..1934074	+	1143	WP_001176863.1	glycerate kinase	-
KI244_RS09725 (KI244_09725)	1934134..1934793	+	660	WP_000831298.1	membrane protein	-
KI244_RS09730 (KI244_09730)	1934975..1936186	+	1212	WP_001192075.1	multidrug effflux MFS transporter	-
KI244_RS09735 (KI244_09735)	1936309..1936782	-	474	WP_000456489.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T204575 WP_000482647.1 NZ_CP076029:c1932144-1932037 [Staphylococcus sp. MZ9]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T204575 NZ_CP101114:968646-968960 [Bartonella harrusi]
ATGATACGTAAAAGAATGAATAAAGGTGATTTGGTGATTGAATCTTTTGCGGATAAGCGATGTAAAGATCTTTTAGAAGG
TAACCCGCCCAGAGGTTTTCCTACAACTTTAGTGCGTATCGCTCAAAGAAAATTGTTTATGCTTGATAAAGCAGTTGATC
TCAAAGATTTACGTAGTCCTCCGGGAAATCGCTTAGAAGCATTGAAAGGAGAACGTAAAGGTCAATATTCTATTCGTATT
AATGACCAGTTTCGTATTTGTTTTGAATGGCGTTCCAATGGCGCCTATGAAGTTGAAATCGTAGATTATCATTGA

Antitoxin

Nucleotide

• Length: 61 bp

>AT204575 NZ_CP076029:1931960-1932020 [Staphylococcus sp. MZ9]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin