Detailed information of TA system TA204569

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1363340..1363522
• Replicon: chromosome
• Accession: NZ_CP076029
• Organism: Staphylococcus sp. MZ9

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: KI244_RS06650
• Protein ID: WP_001801861.1
• Coordinates: 1363340..1363435 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1363463..1363522 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KI244_RS06615 (KI244_06615)	1359010..1359636	+	627	WP_045177256.1	hypothetical protein	-
KI244_RS06620 (KI244_06620)	1359677..1360018	+	342	WP_045177258.1	DUF3969 family protein	-
KI244_RS06625 (KI244_06625)	1360119..1360691	+	573	WP_045177260.1	hypothetical protein	-
KI244_RS06630 (KI244_06630)	1360889..1361517	-	629	Protein_1306	ImmA/IrrE family metallo-endopeptidase	-
KI244_RS06635 (KI244_06635)	1361820..1361996	-	177	WP_000375477.1	hypothetical protein	-
KI244_RS06640 (KI244_06640)	1362007..1362390	-	384	WP_000070811.1	hypothetical protein	-
KI244_RS06645 (KI244_06645)	1362994..1363137	-	144	WP_001549059.1	transposase	-
KI244_RS06650 (KI244_06650)	1363340..1363435	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1363463..1363522	-	60	-	-	Antitoxin
KI244_RS06655 (KI244_06655)	1363558..1363659	+	102	WP_001791893.1	hypothetical protein	-
KI244_RS06660 (KI244_06660)	1363637..1363813	-	177	Protein_1312	transposase	-
KI244_RS06665 (KI244_06665)	1364007..1364384	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	1356451..1395489	39038

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T204569 WP_001801861.1 NZ_CP076029:1363340-1363435 [Staphylococcus sp. MZ9]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T204569 NZ_CP100765:4664217-4664528 [Serratia nematodiphila]
ATGCATATCATTTCCAGGGAACCGTTCAATAACGCAACGAAACAATATCCCAATGAAGCCACTGCTCTCGAGGCCATTTA
TAAAGCGTTGCGACGGGGCGAGTTCCGCACGCCGGACGAGTTAAAAGCGCTTTTTCCTTCGCTCGATCGTATGAAATACA
AAGAGAAATGGTGGGTCATTGACGTCGGCGGCAACCACCTGCGGATCTTGTTCTTTGCCAGCTTCGAGACACAGAAAGTC
TTCATAAAGCATATCGTTAGCCACGCCGAATACGACAAGCTGATGCAGCACTATCGAAGGAGTTCATCATGA

Antitoxin

Nucleotide

• Length: 60 bp

>AT204569 NZ_CP076029:c1363522-1363463 [Staphylococcus sp. MZ9]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin