Detailed information of TA system TA204564

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2514845..2515029
• Replicon: chromosome
• Accession: NZ_CP076028
• Organism: Staphylococcus sp. MZ8

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: KI239_RS12465
• Protein ID: WP_000482647.1
• Coordinates: 2514922..2515029 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2514845..2514905 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KI239_RS12450 (KI239_12450)	2510296..2510463	-	168	WP_001790576.1	hypothetical protein	-
KI239_RS12455 (KI239_12455)	2510694..2512427	-	1734	WP_000486494.1	ABC transporter ATP-binding protein	-
KI239_RS12460 (KI239_12460)	2512452..2514215	-	1764	WP_006191000.1	ABC transporter ATP-binding protein	-
-	2514845..2514905	+	61	-	-	Antitoxin
KI239_RS12465 (KI239_12465)	2514922..2515029	-	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
KI239_RS12470 (KI239_12470)	2515163..2515549	-	387	WP_000779360.1	flippase GtxA	-
KI239_RS12475 (KI239_12475)	2515817..2516959	+	1143	WP_001176863.1	glycerate kinase	-
KI239_RS12480 (KI239_12480)	2517019..2517678	+	660	WP_000831298.1	membrane protein	-
KI239_RS12485 (KI239_12485)	2517860..2519071	+	1212	WP_001192075.1	multidrug effflux MFS transporter	-
KI239_RS12490 (KI239_12490)	2519194..2519667	-	474	WP_000456489.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T204564 WP_000482647.1 NZ_CP076028:c2515029-2514922 [Staphylococcus sp. MZ8]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T204564 NZ_CP100765:c3131584-3131186 [Serratia nematodiphila]
ATGTTCAGCCATATGCTGGACACCAACATTGTTATCTATGTCATCAAGCGCCGGCCGCTGGAAGTGCTGGAGGCGTTCAA
TCGCTATGCGGGCAAAATGGTCATTTCGTCGGTCACCTATGGCGAATTGGTTCACGGAGTGGAGAAAAGCTCGCGTCCGG
CGGTTAACGCCAGAGTGGTTGAGGATTTTGTCTCCCGATTGGACATTCTCGATTACGGCGCCAAAGCGGCTTCGCACTAC
GGCAACATTCGGGCTGCGCTGGAACGTCAGGGAACGCCTATTGGCGTAAACGATCTGCATATCGCCGGGCATGCGCGCAG
CGAAGGATTGATTCTGGTGACCAATAACCGACGCGAATTTGAGCGCGTTGATGGCTTACGGCTGGAAAATTGGCTGTAA

Antitoxin

Nucleotide

• Length: 61 bp

>AT204564 NZ_CP076028:2514845-2514905 [Staphylococcus sp. MZ8]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin