Detailed information of TA system TA204558

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1931460..1931642
• Replicon: chromosome
• Accession: NZ_CP076028
• Organism: Staphylococcus sp. MZ8

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: KI239_RS09320
• Protein ID: WP_001801861.1
• Coordinates: 1931460..1931555 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1931583..1931642 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KI239_RS09285 (KI239_09285)	1927131..1927756	+	626	Protein_1843	hypothetical protein	-
KI239_RS09290 (KI239_09290)	1927797..1928138	+	342	WP_045177258.1	DUF3969 family protein	-
KI239_RS09295 (KI239_09295)	1928239..1928811	+	573	WP_045177260.1	hypothetical protein	-
KI239_RS09300 (KI239_09300)	1929009..1929637	-	629	Protein_1846	ImmA/IrrE family metallo-endopeptidase	-
KI239_RS09305 (KI239_09305)	1929940..1930116	-	177	WP_000375477.1	hypothetical protein	-
KI239_RS09310 (KI239_09310)	1930127..1930510	-	384	WP_000070811.1	hypothetical protein	-
KI239_RS09315 (KI239_09315)	1931114..1931257	-	144	WP_001549059.1	transposase	-
KI239_RS09320 (KI239_09320)	1931460..1931555	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1931583..1931642	-	60	-	-	Antitoxin
KI239_RS09325 (KI239_09325)	1931678..1931779	+	102	WP_001791893.1	hypothetical protein	-
KI239_RS09330 (KI239_09330)	1931757..1931933	-	177	Protein_1852	transposase	-
KI239_RS09335 (KI239_09335)	1932127..1932504	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	1924572..1963608	39036

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T204558 WP_001801861.1 NZ_CP076028:1931460-1931555 [Staphylococcus sp. MZ8]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T204558 NZ_CP100765:460970-461245 [Serratia nematodiphila]
ATGCGTATCGAATGGGATAATGCAGCGCTACGGGACAGGGAACGTATTTTTGAGTTTCTTTATATTTTCAATCCACAGGC
GGCAGTGCAGGCTGATAACGAGATAGATAAAGCGGTAAAGCGCCTGCTGGATCATCCTGAATTAGGTAAGCCTTGGTATG
GGAAGGCACGTAAGCTGCTAGTGGACAAGGCCTCCCTGTTGCTGGTGTATATCATCGTCGATGATGTTATTAAGGTTTTC
TCGATTGCCCACCAGCGCGAGAAATTTCCAAACTAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT204558 NZ_CP076028:c1931642-1931583 [Staphylococcus sp. MZ8]
ACAACGAAAATAAGTATTTACTTATACACCACTCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin