Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2501609..2501793 Replicon chromosome
Accession NZ_CP076027
Organism Staphylococcus sp. MZ7

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag KI234_RS12450 Protein ID WP_000482647.1
Coordinates 2501686..2501793 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2501609..2501669 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KI234_RS12435 (KI234_12435) 2497060..2497227 - 168 WP_001790576.1 hypothetical protein -
KI234_RS12440 (KI234_12440) 2497458..2499191 - 1734 WP_000486494.1 ABC transporter ATP-binding protein -
KI234_RS12445 (KI234_12445) 2499216..2500979 - 1764 WP_006191000.1 ABC transporter ATP-binding protein -
- 2501609..2501669 + 61 - - Antitoxin
KI234_RS12450 (KI234_12450) 2501686..2501793 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
KI234_RS12455 (KI234_12455) 2501927..2502313 - 387 WP_000779360.1 flippase GtxA -
KI234_RS12460 (KI234_12460) 2502581..2503723 + 1143 WP_001176863.1 glycerate kinase -
KI234_RS12465 (KI234_12465) 2503783..2504442 + 660 WP_000831298.1 membrane protein -
KI234_RS12470 (KI234_12470) 2504624..2505835 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
KI234_RS12475 (KI234_12475) 2505958..2506431 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T204553 WP_000482647.1 NZ_CP076027:c2501793-2501686 [Staphylococcus sp. MZ7]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T204553 NZ_CP100764:3216284-3216466 [Serratia plymuthica]
GTGAAAAGTTCAGAACTGATCAGGCTGTTAGAACGAGAAGGTTGGGTTTTAGAGCGGATAAAGGGAAGCCACCATCAGTT
TAAACACCCGAGATCTCGTTTGGTGATCACCGTTCCACACCCGCGTAAAGATCTGAAGCCGGGAACGCTGCGCCAGATCA
TGAAAGATGCCGGGCTGTGCTAA

Antitoxin


Download         Length: 61 bp

>AT204553 NZ_CP076027:2501609-2501669 [Staphylococcus sp. MZ7]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References