Detailed information of TA system TA204547

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1932731..1932913
• Replicon: chromosome
• Accession: NZ_CP076027
• Organism: Staphylococcus sp. MZ7

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: KI234_RS09390
• Protein ID: WP_001801861.1
• Coordinates: 1932731..1932826 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1932854..1932913 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KI234_RS09355 (KI234_09355)	1928401..1929027	+	627	WP_045177256.1	hypothetical protein	-
KI234_RS09360 (KI234_09360)	1929068..1929409	+	342	WP_045177258.1	DUF3969 family protein	-
KI234_RS09365 (KI234_09365)	1929510..1930082	+	573	WP_045177260.1	hypothetical protein	-
KI234_RS09370 (KI234_09370)	1930280..1930908	-	629	Protein_1858	ImmA/IrrE family metallo-endopeptidase	-
KI234_RS09375 (KI234_09375)	1931211..1931387	-	177	WP_000375477.1	hypothetical protein	-
KI234_RS09380 (KI234_09380)	1931398..1931781	-	384	WP_000070811.1	hypothetical protein	-
KI234_RS09385 (KI234_09385)	1932385..1932528	-	144	WP_001549059.1	transposase	-
KI234_RS09390 (KI234_09390)	1932731..1932826	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1932854..1932913	-	60	-	-	Antitoxin
KI234_RS09395 (KI234_09395)	1932949..1933050	+	102	WP_001791893.1	hypothetical protein	-
KI234_RS09400 (KI234_09400)	1933028..1933204	-	177	Protein_1864	transposase	-
KI234_RS09405 (KI234_09405)	1933398..1933775	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	1925842..1964881	39039

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T204547 WP_001801861.1 NZ_CP076027:1932731-1932826 [Staphylococcus sp. MZ7]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T204547 NZ_CP100764:555493-556791 [Serratia plymuthica]
ATGGAAAAGCTACGTGTGGCGCTGAATGGCACTGTTGTTGGGACGCTGGAAAAGCACGCGGGCGGCGCGATGTCGTTTGT
TTACCACGAAGAGTGGCTGGCACAAGCCGGTGCGCGCGCCATATCGTTATCCCTGCCGCTACAACCAGAACCGTTTCGCG
GTGACGTGGTGTATAACTTTTTCGACAACCTGCTGCCGGACAGCGAACTTATTCGCAGCCGCCTACAGGCGCGTTTTAAA
ACGGCAACCAAACAGCCTTTTGATCTGCTTTCCAGCATTGGCAGCGACTGCGTGGGTGCGATCCAGCTTTACCCTGAACA
TGCCGATGTGGCCCCGGTCAAGCAAGTGAACGCCGTGCCTGTCAGTGACGAAGAAATAGAGCAACTTCTGCTGGGGTACC
GCGAGGCACCGCTGGGCATGGAGGCGGGTATTGATGATTTCCGGATCTCTCTGGCGGGTGCGCAGGAAAAGACCGCGCTG
CTTTGGTTCGGCAATCAGTGGTGTCGGCCACAGGGGAGTACGCCAACCAGCCACATCATAAAACTGCCCATTGGGCATAT
TGCACATAACAATTTGGATCTCAGTGAAAGCTGTGAGAACGAGTGGTTATGTTTGCGCATTGCAGAACAGTTTGGCCTGC
CGGTAGCGCAGGCTGAGTTGGCGCATTTTGGCGAGCAGAAGGTCCTGATCGTTGAGCGTTTTGACCGGCGTTGGGCGCGG
GATAACAGTTGGCTGATTCGTTTGCCGCAGGAGGATTTTTGCCAGGCGTTAGGCATTGCTCATGCGCTGAAATATGAGGC
TGATGGTGGGCCCGGTATTGCGGCTGCTATGGAGTTGCTATTGGGCTCTCAACAACCCTTGCTCGATCGGGACATTTTCT
TTAAAAGCCAAATCGTATTCTGGATGCTGGCGGCCATTGATGGGCATGCCAAAAACTTTAGCCTGTTCATTGAGCAGGAA
ACGGCCTATCGAATGACTCCGCTTTACGATGTGCTCTCGGGTTACCCATTCATGAACGCCCGTGGCATCGCGCCGCAGAA
AGCAAAAATGGCCATGGCCGTGCTGGGGCAAAGTCGCCATTACCGTTGGAGCCAGATCTTGCCTCGGCACTTTATCTCTA
CCGCGAGAGCGGTGGGGTATTCCGAAGAGAAAACGCTGCAGGTGATGGCTGAGCTAAAAGCGCAAACGGAGCAGGCGATC
GCTAATGTGGAAGCGATGCTGCCGGATGAGTTTCCTCGTCTCGTGAGTGATGCGATTTTTGCTGGGGTTCGGCGGCAGGC
TGAGAGGTTGGTGGGGTAG

Antitoxin

Nucleotide

• Length: 60 bp

>AT204547 NZ_CP076027:c1932913-1932854 [Staphylococcus sp. MZ7]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin