Detailed information of TA system TA204530

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): SprA2-SprA2AS/-
• Location: 2465683..2465867
• Replicon: chromosome
• Accession: NZ_CP076025
• Organism: Staphylococcus sp. MZ1

Toxin (Protein)

• Gene name: SprA2
• Uniprot ID: A0A2P7CQJ7
• Locus tag: KI229_RS12205
• Protein ID: WP_000482647.1
• Coordinates: 2465760..2465867 (-)
• Length: 36 a.a.

Antitoxin (RNA)

Gene name	SprA2AS
Locus tag	-
Coordinates	2465683..2465743 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KI229_RS12190 (KI229_12190)	2461134..2461301	-	168	WP_001790576.1	hypothetical protein	-
KI229_RS12195 (KI229_12195)	2461532..2463265	-	1734	WP_000486494.1	ABC transporter ATP-binding protein	-
KI229_RS12200 (KI229_12200)	2463290..2465053	-	1764	WP_006191000.1	ABC transporter ATP-binding protein	-
-	2465683..2465743	+	61	-	-	Antitoxin
KI229_RS12205 (KI229_12205)	2465760..2465867	-	108	WP_000482647.1	type I toxin-antitoxin system Fst family toxin	Toxin
KI229_RS12210 (KI229_12210)	2466001..2466387	-	387	WP_000779360.1	flippase GtxA	-
KI229_RS12215 (KI229_12215)	2466655..2467797	+	1143	WP_001176863.1	glycerate kinase	-
KI229_RS12220 (KI229_12220)	2467857..2468516	+	660	WP_000831298.1	membrane protein	-
KI229_RS12225 (KI229_12225)	2468698..2469909	+	1212	WP_001192075.1	multidrug effflux MFS transporter	-
KI229_RS12230 (KI229_12230)	2470032..2470505	-	474	WP_000456489.1	GyrI-like domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 36 a.a.
• Molecular weight: 4012.76 Da
• Isoelectric Point: 10.4935

>T204530 WP_000482647.1 NZ_CP076025:c2465867-2465760 [Staphylococcus sp. MZ1]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Nucleotide

• Length: 108 bp

>T204530 NZ_CP100753:c574675-574331 [Serratia marcescens]
ATGTGGCAAGTGGTGACCGTCGAACGGTTTGACGACTGGTTTTTAGCGCTGAACAACGCCCAGCAAACAAGCATCCTGGC
GGCGATCTACAAATTGCAGACGTTCGGTCCGCAATTGGCGCGGCCGCATGCCGATACGCTGCATTTTTCCGACGCGGTCC
GGCAGTTGAAGGAGCTGCGCATTCAACATCGCGGGCGCCCTTTCAGGGTGTTTTTCGCCTTTGATCCACAGCGGCAAGCG
GTATTGCTGTGCGGCGGCGATAAAACCGGCGACAAACGCTTTTACCAGCGCATGTTGCCCATCGCCGCCATGGAGTTTTC
ACATTATCTGGCAACCCGGAGGTAG

Antitoxin

Nucleotide

• Length: 61 bp

>AT204530 NZ_CP076025:2465683-2465743 [Staphylococcus sp. MZ1]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Structures

Toxin

• AlphaFold DB: A0A2P7CQJ7

Antitoxin