Detailed information of TA system TA204524

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 1882281..1882463
• Replicon: chromosome
• Accession: NZ_CP076025
• Organism: Staphylococcus sp. MZ1

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: KI229_RS09060
• Protein ID: WP_001801861.1
• Coordinates: 1882281..1882376 (+)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	1882404..1882463 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KI229_RS09025 (KI229_09025)	1877951..1878577	+	627	WP_045177256.1	hypothetical protein	-
KI229_RS09030 (KI229_09030)	1878618..1878959	+	342	WP_045177258.1	DUF3969 family protein	-
KI229_RS09035 (KI229_09035)	1879060..1879632	+	573	WP_045177260.1	hypothetical protein	-
KI229_RS09040 (KI229_09040)	1879830..1880458	-	629	Protein_1789	ImmA/IrrE family metallo-endopeptidase	-
KI229_RS09045 (KI229_09045)	1880761..1880937	-	177	WP_000375477.1	hypothetical protein	-
KI229_RS09050 (KI229_09050)	1880948..1881331	-	384	WP_000070811.1	hypothetical protein	-
KI229_RS09055 (KI229_09055)	1881935..1882078	-	144	WP_001549059.1	transposase	-
KI229_RS09060 (KI229_09060)	1882281..1882376	+	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
-	1882404..1882463	-	60	-	-	Antitoxin
KI229_RS09065 (KI229_09065)	1882499..1882600	+	102	WP_001791893.1	hypothetical protein	-
KI229_RS09070 (KI229_09070)	1882578..1882754	-	177	Protein_1795	transposase	-
KI229_RS09075 (KI229_09075)	1882948..1883325	-	378	WP_001037045.1	DUF1433 domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	lukD / hlgA	1875392..1914430	39038

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-84)

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T204524 WP_001801861.1 NZ_CP076025:1882281-1882376 [Staphylococcus sp. MZ1]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T204524 NZ_CP100748:c83212-82928 [Salmonella enterica subsp. enterica serovar Montevideo]
ATGACCTATAAGCTGGCTTTCAACGAATCCGCTCTGAAAGAATGGAAGAAGCTGGGTCATACACTGCAGGTGCAGTTCAA
AAAGAAGCTCAAAGAGCGCCTGGAAAATCCCAGAGTTCCTGCATCACAGCTACATGGACGTAAGGACCAGTATAAAATTA
AGCTACGTGGTGCCGGATACCGCCTTGTCTATCGTGTAGAGGACGACATTGTCACAGTCACTGTTATCGGCGTAGGCAAA
CGCGAAAACGACGACATTTATAATGCAACCCTTAATCGCAATTGA

Antitoxin

Nucleotide

• Length: 60 bp

>AT204524 NZ_CP076025:c1882463-1882404 [Staphylococcus sp. MZ1]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin