Detailed information of TA system TA203981

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): fst-RNAII/Fst(toxin)
• Location: 43315..43558
• Replicon: plasmid p1207_3
• Accession: NZ_CP075607
• Organism: Enterococcus faecalis strain 1207/14

Toxin (Protein)

• Gene name: fst
• Uniprot ID: -
• Locus tag: KKP64_RS17300
• Protein ID: WP_002387930.1
• Coordinates: 43315..43416 (+)
• Length: 34 a.a.

Antitoxin (RNA)

Gene name	RNAII
Locus tag	-
Coordinates	43456..43558 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
KKP64_RS17255 (38431)	38431..38793	-	363	WP_000241511.1	type II toxin-antitoxin system PemK/MazF family toxin	-
KKP64_RS17260 (38787)	38787..39050	-	264	WP_000245205.1	PbsX family transcriptional regulator	-
KKP64_RS17265 (39227)	39227..39847	+	621	WP_021732893.1	recombinase family protein	-
KKP64_RS17270 (39864)	39864..40151	+	288	WP_010708491.1	hypothetical protein	-
KKP64_RS17275 (40145)	40145..40369	+	225	WP_010708492.1	ultraviolet resistance protein UvrA repressor UvrC	-
KKP64_RS17280 (40430)	40430..40639	+	210	WP_002387638.1	hypothetical protein	-
KKP64_RS17805 (40801)	40801..40953	+	153	WP_225850000.1	DUF6440 family protein	-
KKP64_RS17290 (41380)	41380..42708	+	1329	WP_002387639.1	ultraviolet resistance protein UvrA	-
KKP64_RS17295 (42705)	42705..43055	+	351	WP_002365943.1	hypothetical protein	-
KKP64_RS17810 (43012)	43012..43224	+	213	WP_002365945.1	hypothetical protein	-
KKP64_RS17300 (43315)	43315..43416	+	102	WP_002387930.1	type I toxin-antitoxin system Fst family toxin	Toxin
- (43456)	43456..43558	-	103	NuclAT_0	-	Antitoxin
- (43456)	43456..43558	-	103	NuclAT_0	-	Antitoxin
- (43456)	43456..43558	-	103	NuclAT_0	-	Antitoxin
- (43456)	43456..43558	-	103	NuclAT_0	-	Antitoxin
KKP64_RS17305 (43755)	43755..44216	+	462	WP_002365946.1	hypothetical protein	-
KKP64_RS17310 (44387)	44387..44677	+	291	WP_002365947.1	hypothetical protein	-
KKP64_RS17315 (44781)	44781..45152	-	372	WP_000049959.1	replication-associated protein RepC	-
KKP64_RS17320 (45145)	45145..45990	-	846	WP_000239313.1	AAA family ATPase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..46461	46461

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 34 a.a.
• Molecular weight: 3731.42 Da
• Isoelectric Point: 4.1672

>T203981 WP_002387930.1 NZ_CP075607:43315-43416 [Enterococcus faecalis]
VKDLMSLVIAPIFVGLVLEMISRVLDEEDDSRK

Nucleotide

• Length: 102 bp

>T203981 NZ_CP100500:325077-325352 [Escherichia coli]
ATGAGAACCAAGGTACAGGCTTTACGGAAGAAACAAAAAAATACATTGGATCAAATATTTAAAACTCCTGTTCCTCAAGG
GATCAAGTGGTCTGATATAGAGTCACTGGTTAAAGCATTAGGCGGAGAAATTAAGGAAGGAAGAGGTTCGCGTTGTAAGT
TCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGTCGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTG
CGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin

Nucleotide

• Length: 103 bp

>AT203981 NZ_CP075607:c43558-43456 [Enterococcus faecalis]
TTGACCCAAAATAAAAATATGCTATACTAAAAGTGCGAAACGACATTAAATCGTACAGATAACACAAAAAGCAATCCTAC
GGCGAATAGGATTGCTTTTTTTT

Structures

Antitoxin