Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) txpA-RNAII/-
Location 3147629..3147946 Replicon chromosome
Accession NZ_CP075604
Organism Enterococcus faecalis strain 1207/14

Toxin (Protein)


Gene name txpA Uniprot ID C7CYQ7
Locus tag KKP64_RS15690 Protein ID WP_002358966.1
Coordinates 3147749..3147946 (+) Length 66 a.a.

Antitoxin (RNA)


Gene name RNAII
Locus tag -
Coordinates 3147629..3147692 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KKP64_RS15670 3143072..3143704 - 633 WP_002358972.1 RloB family protein -
KKP64_RS15675 3143713..3145008 - 1296 WP_002396787.1 ATP-binding protein -
KKP64_RS15680 3145470..3147086 + 1617 WP_002358967.1 phosphatase PAP2/LCP family protein -
KKP64_RS15685 3147441..3147563 + 123 WP_002404776.1 putative holin-like toxin -
- 3147629..3147692 - 64 - - Antitoxin
KKP64_RS15690 3147749..3147946 + 198 WP_002358966.1 type I toxin-antitoxin system toxin PepG1 Toxin
KKP64_RS15695 3148065..3148205 + 141 WP_077143780.1 putative holin-like toxin -
KKP64_RS15700 3148436..3148579 + 144 WP_002396786.1 putative holin-like toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Small toxic protein BsrE-like

(32-65)


Sequences

Toxin        


Download         Length: 66 a.a.        Molecular weight: 7571.21 Da        Isoelectric Point: 10.8134

>T203957 WP_002358966.1 NZ_CP075604:3147749-3147946 [Enterococcus faecalis]
MCREVMAVAIQSEREVMRMHVFPKFRERRGLLSAYETIQTILGFGMFTIALIALIVKLLKNDKKK

Download         Length: 198 bp

>T203957 NZ_CP100488:2255-2533 [Escherichia coli]
ATGGAGATATTCTGGACCATGCTGGCCAGCCAGGACAGGAAGCGCATTCGTGAGTACATTGCGGAGCAGAACCTGATGGC
CGCCATTGAACTGGACGAGCGGATTGGTTATTCAGCCAGCAGCCTGGCCGGGCAGCCGTATAAAGGCCGCAATGGTCGTG
TGGAAGGTACCCGGGAACTGGTTATTCACCCGCATTTTGTTCTGGTTTATGAGGTCGACAGCCAGTGGGGAAAAGTGTAT
ATCCTGCGCGTGTTGCATACTGCACAGAAGTGGCCATAG

Antitoxin


Download         Length: 64 bp

>AT203957 NZ_CP075604:c3147692-3147629 [Enterococcus faecalis]
TTGTGCTATAATAGCAATGAAAAGAGAGATATGCTGTAACATACCTCTCTAGTGTAGAGCCGTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB C7CYQ7

Antitoxin

Download structure file

References