Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) sprG-sprF/-
Location 2206432..2206648 Replicon chromosome
Accession NC_002745
Organism Staphylococcus aureus subsp. aureus N315

Toxin (Protein)


Gene name SprG3 Uniprot ID Q2FWA7
Locus tag SA_RS11230 Protein ID WP_001802298.1
Coordinates 2206544..2206648 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name SprF1
Locus tag -
Coordinates 2206432..2206487 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SA_RS11210 (SA1953) 2201983..2202360 - 378 WP_000361059.1 transposase -
SA_RS11215 (SA1954) 2202367..2204259 - 1893 WP_001557544.1 site-specific integrase -
SA_RS11220 (SA1955) 2204256..2205341 - 1086 WP_000868132.1 tyrosine-type recombinase/integrase -
SA_RS11225 (SA1956) 2205467..2206111 + 645 Protein_2097 transcriptional regulator -
- 2206432..2206487 + 56 - - Antitoxin
SA_RS11230 2206544..2206648 - 105 WP_001802298.1 hypothetical protein Toxin
SA_RS14875 2207328..2207486 + 159 WP_001792784.1 hypothetical protein -
SA_RS11235 (SA1957) 2208144..2209001 - 858 WP_000370925.1 Cof-type HAD-IIB family hydrolase -
SA_RS11240 (SA1958) 2209069..2209851 - 783 WP_000908182.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3906.77 Da        Isoelectric Point: 5.5724

>T20393 WP_001802298.1 NC_002745:c2206648-2206544 [Staphylococcus aureus subsp. aureus N315]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T20393 NC_002745:c2206648-2206544 [Staphylococcus aureus subsp. aureus N315]
TTGTTACTCCTAGAAAGGACTAGCATGTCTGATTTTGAAATGCTGATGGTTGTATTAACAATCATTGGTTTAGTATTGAT
TAGTACTCAAGACCATAAAAAATAA

Antitoxin


Download         Length: 56 bp

>AT20393 NC_002745:2206432-2206487 [Staphylococcus aureus subsp. aureus N315]
AAAAAGGGCAACACTCGGAAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2I7Y9L9

Antitoxin

Download structure file

References