Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | sprG-sprF/- |
| Location | 128557..128782 | Replicon | chromosome |
| Accession | NZ_CP075562 | ||
| Organism | Staphylococcus aureus strain Sta2021010 | ||
Toxin (Protein)
| Gene name | SprG2 | Uniprot ID | - |
| Locus tag | KI818_RS00660 | Protein ID | WP_000253687.1 |
| Coordinates | 128557..128664 (+) | Length | 36 a.a. |
Antitoxin (RNA)
| Gene name | SprF3 | ||
| Locus tag | - | ||
| Coordinates | 128689..128782 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KI818_RS00640 (124519) | 124519..125634 | + | 1116 | WP_031886335.1 | hypothetical protein | - |
| KI818_RS00645 (125650) | 125650..127836 | + | 2187 | WP_031886334.1 | phage tail protein | - |
| KI818_RS00650 (127823) | 127823..127972 | + | 150 | WP_162783876.1 | hypothetical protein | - |
| KI818_RS00655 (128021) | 128021..128320 | + | 300 | WP_031886333.1 | DUF2951 domain-containing protein | - |
| KI818_RS00660 (128557) | 128557..128664 | + | 108 | WP_000253687.1 | putative holin-like toxin | Toxin |
| - (128689) | 128689..128782 | - | 94 | NuclAT_1 | - | Antitoxin |
| - (128689) | 128689..128782 | - | 94 | NuclAT_1 | - | Antitoxin |
| - (128689) | 128689..128782 | - | 94 | NuclAT_1 | - | Antitoxin |
| - (128689) | 128689..128782 | - | 94 | NuclAT_1 | - | Antitoxin |
| KI818_RS00665 (128704) | 128704..128811 | - | 108 | Protein_128 | hypothetical protein | - |
| KI818_RS00670 (128862) | 128862..129299 | + | 438 | WP_031886332.1 | phage holin | - |
| KI818_RS00675 (129280) | 129280..130725 | + | 1446 | WP_234494763.1 | SH3 domain-containing protein | - |
| KI818_RS00680 (131254) | 131254..131460 | + | 207 | WP_000125170.1 | hypothetical protein | - |
| KI818_RS00685 (131475) | 131475..131675 | + | 201 | WP_000498229.1 | hypothetical protein | - |
| KI818_RS00690 (131738) | 131738..131872 | - | 135 | Protein_133 | dihydrolipoamide dehydrogenase | - |
| KI818_RS00695 (131859) | 131859..132299 | - | 441 | WP_001047238.1 | redox-sensitive transcriptional regulator HypR | - |
| KI818_RS00700 (132357) | 132357..132458 | + | 102 | WP_001788276.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 95632..131675 | 36043 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 36 a.a. Molecular weight: 3844.80 Da Isoelectric Point: 10.4997
>T203870 WP_000253687.1 NZ_CP075562:128557-128664 [Staphylococcus aureus]
VVSIVDALNLMFSFGMFIVTLLGLVIAIVKLNHKK
VVSIVDALNLMFSFGMFIVTLLGLVIAIVKLNHKK
Download Length: 108 bp
>T203870 NZ_CP100430:c1456340-1456158 [Streptococcus suis]
ATGCCTATGACACAAAAAGAAATGGTTAAACTTCTTACCGCCAACGGTTGGACAAAGACCAAAGGCGGTAAAGGGTCACA
CGTTAAACTTGAAAAAGCAGGCGAGCGACCTATAACCATTCCCCACGGTGAAATTAACAAATACACCGAAAGGGGTATCA
AAAAGCAAGCAGGGCTGTTATAA
ATGCCTATGACACAAAAAGAAATGGTTAAACTTCTTACCGCCAACGGTTGGACAAAGACCAAAGGCGGTAAAGGGTCACA
CGTTAAACTTGAAAAAGCAGGCGAGCGACCTATAACCATTCCCCACGGTGAAATTAACAAATACACCGAAAGGGGTATCA
AAAAGCAAGCAGGGCTGTTATAA
Antitoxin
Download Length: 94 bp
>AT203870 NZ_CP075562:c128782-128689 [Staphylococcus aureus]
ATAAATAGAAAAAGGGCAACATGCGGAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGACCTCTTTTATATGAT
TAATAAATAACCAT
ATAAATAGAAAAAGGGCAACATGCGGAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGACCTCTTTTATATGAT
TAATAAATAACCAT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
