Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/RelE-MqsA
Location 3733015..3733606 Replicon chromosome
Accession NZ_CP074570
Organism Paraneptunicella aestuarii strain NBU2194

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag KIH87_RS14305 Protein ID WP_232358533.1
Coordinates 3733295..3733606 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag KIH87_RS14300 Protein ID WP_232358532.1
Coordinates 3733015..3733302 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KIH87_RS14280 (KIH87_14340) 3728283..3730286 - 2004 WP_232358531.1 excinuclease ABC subunit UvrB -
KIH87_RS14285 (KIH87_14345) 3730286..3731608 - 1323 WP_232361495.1 MATE family efflux transporter -
KIH87_RS14300 (KIH87_14360) 3733015..3733302 - 288 WP_232358532.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
KIH87_RS14305 (KIH87_14365) 3733295..3733606 - 312 WP_232358533.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
KIH87_RS14310 (KIH87_14370) 3733860..3736274 + 2415 WP_232358534.1 zinc-dependent metalloprotease -
KIH87_RS14315 (KIH87_14375) 3736430..3737110 + 681 WP_232358535.1 hypothetical protein -
KIH87_RS14320 (KIH87_14380) 3737123..3737551 + 429 WP_232358536.1 hypothetical protein -
KIH87_RS14325 (KIH87_14385) 3737773..3738357 + 585 WP_232358537.1 electron transport complex subunit RsxA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-95)

Antitoxin

Antitoxin MqsA/HigA-2

(30-95)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11922.69 Da        Isoelectric Point: 8.3191

>T202407 WP_232358533.1 NZ_CP074570:c3733606-3733295 [Paraneptunicella aestuarii]
MIFIETSLFTKMLPDYLNDEDYRNLQSYLLQKPDAGDIVKGTGGVRKVRWALEGKGKSGGVRAIYYWKKSEYEIWMLTIY
SKSERTTIPSHILKQIAEAIDNE

Download         Length: 312 bp

>T202407 NZ_CP099386:2348391-2348579 [Citrobacter braakii]
GTGAAGCAAAGTGAGTTCAGACGCTGGCTTGAATCTCAGGGAGTGGCTGTTACAAACGGCTCAAATCATCTGAAGTTGAG
GTATCAGGGAAGGCGTAGCGTTATGCCCAGGCATCCTGGTGATGAAATAAAAGAAGCCTTGCGAAAATCGATCCTGAAGC
AGCTTGGTTTACAGTCATCATCAATATGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10629.20 Da        Isoelectric Point: 10.5573

>AT202407 WP_232358532.1 NZ_CP074570:c3733302-3733015 [Paraneptunicella aestuarii]
MSNRDIGAEILEGIKEIKDFKKGKASLRTTELSQPSPPKEIRKKMNLSQSAFAGLLGVSLRTLQDWEQGRRNPQGSAIAL
LRIAEQHPEVFSDLR

Download         Length: 288 bp

>AT202407 NZ_CP099386:2348611-2349027 [Citrobacter braakii]
ATGCGTTATCCCGTTAATCTAATCCCCGCCGTGGAAGGTGGATTCGTGGTTTCTTTCCCGGATATTCCTGAAGCATTAAC
CCAGGGCGAAACCCGTCATGGGGCTTTGCAGGCTGCGCAGTCTGCATTGGTGACCGCTTTTGAATTCTATTTCGACGATA
ACGAACCGATTCCTTTACCTTCGGCGGTTGGCACTGAAGGTGACTATGTGGAAATCCCCCTGAGCATTGCGTCGAAGGTT
CTTTTGTTAAATGCCTTTCTTGAATCAAAAATCACCCAGCAGGAGCTGGCAAACAGGATTGGCAGGCCTAAGCAGGAAAT
TACCCGTTTGTTCGATTTAAAGCACGCGACAAAAATTGATGCTGTGCAAATAGCTGCACGCGCCTTAGGCAAGGAGCTGT
CAGTAACGATGTTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References