Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | hok-sok/- |
| Location | 8919..9183 | Replicon | plasmid p14523A |
| Accession | NZ_CP074429 | ||
| Organism | Salmonella sp. SJTUF14523 | ||
Toxin (Protein)
| Gene name | pndA | Uniprot ID | U9Z417 |
| Locus tag | KFD69_RS22670 | Protein ID | WP_001387489.1 |
| Coordinates | 9031..9183 (+) | Length | 51 a.a. |
Antitoxin (RNA)
| Gene name | pndB | ||
| Locus tag | - | ||
| Coordinates | 8919..8979 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFD69_RS22655 (5021) | 5021..6091 | - | 1071 | WP_012783932.1 | IncI1-type conjugal transfer protein TrbB | - |
| KFD69_RS22660 (6110) | 6110..7318 | - | 1209 | WP_001703845.1 | IncI1-type conjugal transfer protein TrbA | - |
| - (7498) | 7498..7555 | - | 58 | NuclAT_1 | - | - |
| - (7498) | 7498..7555 | - | 58 | NuclAT_1 | - | - |
| - (7498) | 7498..7555 | - | 58 | NuclAT_1 | - | - |
| - (7498) | 7498..7555 | - | 58 | NuclAT_1 | - | - |
| KFD69_RS22665 (7625) | 7625..8404 | - | 780 | WP_275450201.1 | protein FinQ | - |
| - (8919) | 8919..8979 | - | 61 | NuclAT_0 | - | Antitoxin |
| - (8919) | 8919..8979 | - | 61 | NuclAT_0 | - | Antitoxin |
| - (8919) | 8919..8979 | - | 61 | NuclAT_0 | - | Antitoxin |
| - (8919) | 8919..8979 | - | 61 | NuclAT_0 | - | Antitoxin |
| KFD69_RS22670 (9031) | 9031..9183 | + | 153 | WP_001387489.1 | Hok/Gef family protein | Toxin |
| KFD69_RS22675 (9255) | 9255..9506 | - | 252 | WP_001291964.1 | hypothetical protein | - |
| KFD69_RS24035 (10007) | 10007..10102 | + | 96 | WP_000609148.1 | DinQ-like type I toxin DqlB | - |
| KFD69_RS22685 (10167) | 10167..10343 | - | 177 | WP_001054900.1 | hypothetical protein | - |
| KFD69_RS22690 (10735) | 10735..10944 | + | 210 | WP_000062603.1 | HEAT repeat domain-containing protein | - |
| KFD69_RS22695 (11016) | 11016..11678 | - | 663 | WP_012783935.1 | plasmid IncI1-type surface exclusion protein ExcA | - |
| KFD69_RS22700 (11749) | 11749..13917 | - | 2169 | WP_015508354.1 | DotA/TraY family protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Conjugative plasmid | blaCTX-M-101 | - | 1..85862 | 85862 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 51 a.a. Molecular weight: 5761.10 Da Isoelectric Point: 8.7948
>T202132 WP_001387489.1 NZ_CP074429:9031-9183 [Salmonella sp. SJTUF14523]
MPQRTFLMMLIVVCVTILCFVWMVRDSLCGLRLQQGNTVLVATLAYEVKR
MPQRTFLMMLIVVCVTILCFVWMVRDSLCGLRLQQGNTVLVATLAYEVKR
Download Length: 153 bp
>T202132 NZ_CP099325:c1088422-1088204 [Enterobacter ludwigii]
ATGTCTGAAAAACCACTCACAAAAATCGATTATTTGATGCGTTTGCGACGCTGTCAGTCAATAGACACGCTTGAACGTGT
AATTGAAAAGAATAAATACGAGCTTTCTGATAATGAACTGGCGGTATTTTATTCAGCGGCTGACCACCGTCTTGCAGAAC
TGACTATGAATAAGCTGTATGACAAAATCCCAACGTCCGTGTGGAGATTTGTCCGTTAA
ATGTCTGAAAAACCACTCACAAAAATCGATTATTTGATGCGTTTGCGACGCTGTCAGTCAATAGACACGCTTGAACGTGT
AATTGAAAAGAATAAATACGAGCTTTCTGATAATGAACTGGCGGTATTTTATTCAGCGGCTGACCACCGTCTTGCAGAAC
TGACTATGAATAAGCTGTATGACAAAATCCCAACGTCCGTGTGGAGATTTGTCCGTTAA
Antitoxin
Download Length: 61 bp
>AT202132 NZ_CP074429:c8979-8919 [Salmonella sp. SJTUF14523]
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
GAGGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
