Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) DinJ-YafQ (relBE)/YafQ-RelB
Location 2875848..2876412 Replicon chromosome
Accession NZ_CP074379
Organism Lacticaseibacillus zeae strain FBL8

Toxin (Protein)


Gene name yafQ Uniprot ID -
Locus tag KG087_RS13535 Protein ID WP_010490726.1
Coordinates 2876110..2876412 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID -
Locus tag KG087_RS13530 Protein ID WP_010490728.1
Coordinates 2875848..2876117 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KG087_RS13500 (KG087_13500) 2871049..2872518 - 1470 WP_075761272.1 FGGY-family carbohydrate kinase -
KG087_RS13505 (KG087_13505) 2872673..2873233 - 561 WP_010490738.1 glycerol-3-phosphate responsive antiterminator -
KG087_RS13510 (KG087_13510) 2873382..2874500 - 1119 WP_010490736.1 glycerol dehydrogenase -
KG087_RS13515 (KG087_13515) 2874518..2874736 - 219 WP_010490734.1 hypothetical protein -
KG087_RS13520 (KG087_13520) 2875205..2875390 + 186 WP_010490732.1 hypothetical protein -
KG087_RS13525 (KG087_13525) 2875405..2875680 - 276 WP_010490731.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
KG087_RS13530 (KG087_13530) 2875848..2876117 + 270 WP_010490728.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
KG087_RS13535 (KG087_13535) 2876110..2876412 + 303 WP_010490726.1 type II toxin-antitoxin system YafQ family toxin Toxin
KG087_RS13540 (KG087_13540) 2876782..2877588 + 807 WP_010490725.1 manganese catalase family protein -
KG087_RS13545 (KG087_13545) 2878168..2879847 + 1680 WP_075761361.1 alpha-glucosidase -
KG087_RS13550 (KG087_13550) 2880426..2880545 - 120 WP_010490723.1 putative holin-like toxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-97)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(10-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11488.19 Da        Isoelectric Point: 10.3993

>T202007 WP_010490726.1 NZ_CP074379:2876110-2876412 [Lacticaseibacillus zeae]
MYSLTPTPTFKRDVKRLAKKHWPLDDLKTAINLLVTGTNAETLRSRYADHALSSSSDWRGYRELHVNGPKGDWLLIYKVE
QQNLLLTLVRTGSHKDLLGR

Download         Length: 303 bp

>T202007 NZ_CP099254:4463593-4463880 [Citrobacter freundii]
ATGAGTTATACGGTAAAGTTCAGGGAAGATGCGCTGAAAGAATGGCAAAAATTGGATAAAACCATTCAGCAGCAGTTTGC
CAAAAAACTCAAGAAATGCGGTGAAAATCCGCATGTCCCCTCCGCGAAGCTCAGGGGAATAAAAGATTGCTATAAAATCA
AACTACGCACTTCAGGGTTTCGTCTTGTTTATCAAGTTATTGACGACACCCTGGTCATCGCTGTCGTTGCCGTCGGTAAA
CGCGAGCGTAGTGAAGTTTATAATCTTGCCAGCGAAAGACTGCGCTAA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10056.62 Da        Isoelectric Point: 5.1342

>AT202007 WP_010490728.1 NZ_CP074379:2875848-2876117 [Lacticaseibacillus zeae]
MATTKKETRLNIRIDPELKEAAQDVASDMGIDLSAAVNMFIVKMVKDHALPFTPTSLPVETLQALKEAKHSDKLKKYRTP
DDMWEDLDV

Download         Length: 270 bp

>AT202007 NZ_CP099254:4463345-4463596 [Citrobacter freundii]
ATGCCACATATCATTTTAAGCGACACCACCGCCAGCGTGAGTGAGCTAAAAAAGAACCCGATGGCGACTGTTAGCGCAGG
GGATGGGTTTCCGGTCGCAATCCTGAACCGTAACCAGCCTGCCTTTTATTGTGTTCCCGCTGAGCTTTACGAAAAAATGC
TTGATGCGCTGGACGATCAGCAACTGGTTAAATTAGTCCATGAACGGAACCAACAGCCACTGGTGGATGTTGATCTGGAC
AGCTATTTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References