Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | HipBST/HipA(toxin) |
| Location | 164447..165801 | Replicon | chromosome |
| Accession | NZ_CP074352 | ||
| Organism | Siccibacter colletis strain YSD YN2 | ||
Toxin (Protein)
| Gene name | HipT | Uniprot ID | - |
| Locus tag | KFZ77_RS00810 | Protein ID | WP_264385196.1 |
| Coordinates | 164758..165801 (+) | Length | 348 a.a. |
Antitoxin (Protein)
| Gene name | HipS | Uniprot ID | - |
| Locus tag | KFZ77_RS00805 | Protein ID | WP_264385195.1 |
| Coordinates | 164447..164758 (+) | Length | 104 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| KFZ77_RS00780 (KFZ77_00785) | 159944..160963 | + | 1020 | WP_031522002.1 | dipeptide ABC transporter permease DppB | - |
| KFZ77_RS00785 (KFZ77_00790) | 160973..161875 | + | 903 | WP_264385192.1 | dipeptide ABC transporter permease DppC | - |
| KFZ77_RS00790 (KFZ77_00795) | 161887..162879 | + | 993 | WP_264385193.1 | dipeptide ABC transporter ATP-binding protein | - |
| KFZ77_RS00795 (KFZ77_00800) | 162866..163882 | + | 1017 | WP_031521997.1 | peptide ABC transporter ATP-binding protein | - |
| KFZ77_RS00800 (KFZ77_00805) | 164205..164462 | + | 258 | WP_264385194.1 | helix-turn-helix domain-containing protein | - |
| KFZ77_RS00805 (KFZ77_00810) | 164447..164758 | + | 312 | WP_264385195.1 | HipA N-terminal domain-containing protein | Antitoxin |
| KFZ77_RS00810 (KFZ77_00815) | 164758..165801 | + | 1044 | WP_264385196.1 | HipA domain-containing protein | Toxin |
| KFZ77_RS00815 (KFZ77_00820) | 165878..166063 | - | 186 | WP_264385197.1 | toxin-antitoxin system HicB family antitoxin | - |
| KFZ77_RS00820 (KFZ77_00825) | 166232..166636 | - | 405 | WP_031521986.1 | tRNA(fMet)-specific endonuclease VapC | - |
| KFZ77_RS00825 (KFZ77_00830) | 166636..166866 | - | 231 | WP_031521984.1 | type II toxin-antitoxin system VapB family antitoxin | - |
| KFZ77_RS00830 (KFZ77_00835) | 167050..168735 | - | 1686 | WP_031521983.1 | cellulose biosynthesis protein BcsG | - |
| KFZ77_RS00835 (KFZ77_00840) | 168728..168922 | - | 195 | WP_031521981.1 | cellulose biosynthesis protein BcsF | - |
| KFZ77_RS00840 (KFZ77_00845) | 168919..170484 | - | 1566 | WP_264385198.1 | cellulose biosynthesis protein BcsE | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 348 a.a. Molecular weight: 38745.57 Da Isoelectric Point: 5.7562
>T201854 WP_264385196.1 NZ_CP074352:164758-165801 [Siccibacter colletis]
MALCRILLTPLNARDEATGYSARGLKRLTGTGRASPQLPFTRNEFISELPKAQAGMSISGYQPKLQMIVEKGVFNVVEHQ
GEYILKPSPAEFPFLAENEHATMTLMARLGFDVPPHGLVRFTKAQPGDPEEYAFVIRRYDRDEQGNALHQEQLDAAMDIG
EKYGKTAADGKQYVSYERLATFLLANVNDNLAFKIDLFRRIAYAYLLGNNDMHLRNFGLILPPLGKPELAPIYDFVSVAP
YPPVFNSGFLALPLLRCEEGDGELAPGMKTQYGEYLGKDFLVLGEAMGLAKPVVLRLFAQMQSEARTVEAVYRASFMPAG
DSERVLQCYQQRLKRMMNVDEAEMVGT
MALCRILLTPLNARDEATGYSARGLKRLTGTGRASPQLPFTRNEFISELPKAQAGMSISGYQPKLQMIVEKGVFNVVEHQ
GEYILKPSPAEFPFLAENEHATMTLMARLGFDVPPHGLVRFTKAQPGDPEEYAFVIRRYDRDEQGNALHQEQLDAAMDIG
EKYGKTAADGKQYVSYERLATFLLANVNDNLAFKIDLFRRIAYAYLLGNNDMHLRNFGLILPPLGKPELAPIYDFVSVAP
YPPVFNSGFLALPLLRCEEGDGELAPGMKTQYGEYLGKDFLVLGEAMGLAKPVVLRLFAQMQSEARTVEAVYRASFMPAG
DSERVLQCYQQRLKRMMNVDEAEMVGT
Download Length: 1044 bp
>T201854 NZ_CP098801:233021-233548 [Rhizobium anhuiense bv. trifolii]
ATGACTTTACCTGCATGGCATGAGGAACCGATCGCCAAGTCTCACGGTCGGGCGGCCTTCGATTGCGGCGACGCTCAGAT
GAACGAGTTCCTGCTCCGCTTTGCCCGACAAAGCCATGAGCAGAATGCCTCGAAGACCTTCTGTGCTATCGACGACGCAG
TGCGCGACCGCATTCTTGGGTTCTATACAATCGCGCCTTCGGCAGTCGAGCACGCAACTGTGCCTGATGCAATGACACGC
GGTCTTGCCCGCCATGATGTGCCGGGCTTCAAGCTCGCGCGATTGGCTACCGACCGAGCGGTTTCCGGACAGGGACTGGG
AGGCCAGCTCCTAGCTGCCGCAGCGCTCCGCTGCCTACGACTTGCAGGAGAGGGCGGGGGACTTCTATTGATCATCGATG
CCAAAGGCGAGCGCGCCGCCAACTGGTACGCTTCCTATGGCGCCGAACCGCTGAAGGACAAGCCGCTGACTCTCGTGATG
CCGCTCATCACCTTCGCGGCCGACTTGCGGGCTAAACGTCTTCTTTGA
ATGACTTTACCTGCATGGCATGAGGAACCGATCGCCAAGTCTCACGGTCGGGCGGCCTTCGATTGCGGCGACGCTCAGAT
GAACGAGTTCCTGCTCCGCTTTGCCCGACAAAGCCATGAGCAGAATGCCTCGAAGACCTTCTGTGCTATCGACGACGCAG
TGCGCGACCGCATTCTTGGGTTCTATACAATCGCGCCTTCGGCAGTCGAGCACGCAACTGTGCCTGATGCAATGACACGC
GGTCTTGCCCGCCATGATGTGCCGGGCTTCAAGCTCGCGCGATTGGCTACCGACCGAGCGGTTTCCGGACAGGGACTGGG
AGGCCAGCTCCTAGCTGCCGCAGCGCTCCGCTGCCTACGACTTGCAGGAGAGGGCGGGGGACTTCTATTGATCATCGATG
CCAAAGGCGAGCGCGCCGCCAACTGGTACGCTTCCTATGGCGCCGAACCGCTGAAGGACAAGCCGCTGACTCTCGTGATG
CCGCTCATCACCTTCGCGGCCGACTTGCGGGCTAAACGTCTTCTTTGA
Antitoxin
Download Length: 104 a.a. Molecular weight: 11718.48 Da Isoelectric Point: 7.3568
>AT201854 WP_264385195.1 NZ_CP074352:164447-164758 [Siccibacter colletis]
MLRRVTVRLYGEPVGVLEQSDAGFCFTYHADYQGPPLSLSLPVSQRRFPRATLHPFFVSLAPEGWLKRRYSQIQHLDEKD
LLGMLIHNGKNLIGAVQIEPEEA
MLRRVTVRLYGEPVGVLEQSDAGFCFTYHADYQGPPLSLSLPVSQRRFPRATLHPFFVSLAPEGWLKRRYSQIQHLDEKD
LLGMLIHNGKNLIGAVQIEPEEA
Download Length: 312 bp
>AT201854 NZ_CP098801:232746-233024 [Rhizobium anhuiense bv. trifolii]
ATGCCGAGTATAGCGAACGAGAACAGTGAGCGTATGAGTTTGAGGGTGCCTGCCACGGCCAAGGCTAAGCTCGTGCGCGC
TGCGGCACTTCGTAATACCGATCTGACGAATTTCGTAACCCAATCCGCACTGCGAGAAGCAGAAGCTGTGATCGAAGAAG
CCGAAACGATCAAAGTGTCAGAGCGCGATCATCTTCGCATTCTTGAGCTTCTGGAAAATCCGCCCAAACCCAACGCCAAG
CTGCGCGCGGCGATTGCCGGTTTGCCGGACAGCCTATGA
ATGCCGAGTATAGCGAACGAGAACAGTGAGCGTATGAGTTTGAGGGTGCCTGCCACGGCCAAGGCTAAGCTCGTGCGCGC
TGCGGCACTTCGTAATACCGATCTGACGAATTTCGTAACCCAATCCGCACTGCGAGAAGCAGAAGCTGTGATCGAAGAAG
CCGAAACGATCAAAGTGTCAGAGCGCGATCATCTTCGCATTCTTGAGCTTCTGGAAAATCCGCCCAAACCCAACGCCAAG
CTGCGCGCGGCGATTGCCGGTTTGCCGGACAGCCTATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|