Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 141211..141924 Replicon chromosome
Accession NZ_CP074352
Organism Siccibacter colletis strain YSD YN2

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag KFZ77_RS00695 Protein ID WP_264385181.1
Coordinates 141613..141924 (-) Length 104 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag KFZ77_RS00690 Protein ID WP_264385180.1
Coordinates 141211..141612 (-) Length 134 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KFZ77_RS00670 (KFZ77_00675) 136351..137262 + 912 WP_031522039.1 glycine--tRNA ligase subunit alpha -
KFZ77_RS00675 (KFZ77_00680) 137272..139341 + 2070 WP_264385178.1 glycine--tRNA ligase subunit beta -
KFZ77_RS00680 (KFZ77_00685) 139749..140039 - 291 WP_031522035.1 HTH-type transcriptional regulator -
KFZ77_RS00685 (KFZ77_00690) 140455..141165 + 711 WP_264385179.1 DUF3053 domain-containing protein -
KFZ77_RS00690 (KFZ77_00695) 141211..141612 - 402 WP_264385180.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
KFZ77_RS00695 (KFZ77_00700) 141613..141924 - 312 WP_264385181.1 type II toxin-antitoxin system MqsR family toxin Toxin
KFZ77_RS00700 (KFZ77_00705) 142081..143055 - 975 WP_264385182.1 glyoxylate/hydroxypyruvate reductase GhrB -
KFZ77_RS00705 (KFZ77_00710) 143119..144399 - 1281 WP_264385183.1 MFS transporter -
KFZ77_RS00710 (KFZ77_00715) 144489..145430 - 942 WP_264385184.1 sugar kinase -
KFZ77_RS00715 (KFZ77_00720) 145434..146183 - 750 WP_264385185.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase toxin MqsR

(7-102)

Antitoxin

Cro/C1-type helix-turn-helix domain

(74-125)


Sequences

Toxin        


Download         Length: 104 a.a.        Molecular weight: 11881.72 Da        Isoelectric Point: 7.0599

>T201853 WP_264385181.1 NZ_CP074352:c141924-141613 [Siccibacter colletis]
MVNEKWTPHTRLHVVKQLVLDGKVRTTGSALRHALAAGYREPALQQMCDVILRLQPDDFYKSMTTLADHRIWQDVWHGHD
GDTALYIKLTVIDDLLIVSYKEL

Download         Length: 312 bp

>T201853 NZ_CP098796:91615-91902 [Acinetobacter baumannii]
ATGGAACAGTATTTTGAATGGGATGAGGCTAAGAATCGAAAGAATCAGAAAAAGCATGATATCTCTTTCGAAACTGCAAG
CCTTGTTTTTGAAGATCCATTACGGATCTCAATCCAAGACAGACATACCGATGGTGAAGAACGTTGGCAAACCATTGGAC
GAGTTAAAGGCGTACTAATGTTATTGGTGGCTCACACCATTTTTGATGAAGATGACTGTGAAATCATACGAATCATTAGT
GCAAGGCAAGTGACTAAAGCGGAGCGAAACAAATATGAGCATGGTTAG

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14828.29 Da        Isoelectric Point: 8.6359

>AT201853 WP_264385180.1 NZ_CP074352:c141612-141211 [Siccibacter colletis]
MKCPVCGGAELIHDTRDIPWVYKGQQSLLPAITGDYCPCCGEIILNEEQSNRYARAIREAKKAINARHIDPAFIARIRQK
MALDQREAAALFGGGANAFSRYETGKTQPPLAMIKLFKLLDKHPELMAEVKTL

Download         Length: 402 bp

>AT201853 NZ_CP098796:91889-92203 [Acinetobacter baumannii]
ATGAGCATGGTTAGATACTCACGCAAAGAGCTGAATGAGAAATTTGGTGAGAAGCAAGATGCTGAAATTCAACGCTTGCT
TGCTAAAGGCACGGTTCCTGATGATCAGCTAGATCTATCAGATATTCCTGAAATTACCGATTGGAGCAGTGCTGTACGCC
AAAATCAATTTTACCGCCCAGTGAAGCAACAAACTTCAATTCGGTTAGATGCTGATGTACTTGCTTGGTTCAAAGCACAA
GGCAAAGGTTATCAAACACGAATGAATGAAATTTTACGGGATGCTATGCTGAAAGAATTAAAAAATCATCAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References