Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | yefM-yoeB (relBE)/Txe-YefM |
Location | 702489..702991 | Replicon | chromosome |
Accession | NZ_CP074200 | ||
Organism | Halomonas sp. FeN2 |
Toxin (Protein)
Gene name | yoeB | Uniprot ID | - |
Locus tag | KF947_RS03320 | Protein ID | WP_133732765.1 |
Coordinates | 702489..702752 (-) | Length | 88 a.a. |
Antitoxin (Protein)
Gene name | yefM | Uniprot ID | - |
Locus tag | KF947_RS03325 | Protein ID | WP_133732766.1 |
Coordinates | 702749..702991 (-) | Length | 81 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KF947_RS03300 (KF947_03300) | 698396..698719 | + | 324 | WP_007113240.1 | thioredoxin | - |
KF947_RS03305 (KF947_03305) | 698790..699893 | - | 1104 | WP_133732762.1 | AI-2E family transporter | - |
KF947_RS03310 (KF947_03310) | 700097..700954 | + | 858 | WP_227405444.1 | SIMPL domain-containing protein | - |
KF947_RS03315 (KF947_03315) | 700899..702176 | - | 1278 | WP_227405445.1 | serine--tRNA ligase | - |
KF947_RS03320 (KF947_03320) | 702489..702752 | - | 264 | WP_133732765.1 | Txe/YoeB family addiction module toxin | Toxin |
KF947_RS03325 (KF947_03325) | 702749..702991 | - | 243 | WP_133732766.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
KF947_RS03330 (KF947_03330) | 703339..704586 | + | 1248 | WP_133732767.1 | dicarboxylate/amino acid:cation symporter | - |
KF947_RS03335 (KF947_03335) | 704742..705332 | + | 591 | WP_227405446.1 | DUF4202 domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 88 a.a. Molecular weight: 10040.72 Da Isoelectric Point: 10.0702
>T201800 WP_133732765.1 NZ_CP074200:c702752-702489 [Halomonas sp. FeN2]
VTWKLVYTKHAQKDAKKLASSGLKPKAQELLALIAEDPYRKPPPFEKLIGDLAGAYSRRINIQHRLVYQVLEDEGVIKVL
RLWSHYE
VTWKLVYTKHAQKDAKKLASSGLKPKAQELLALIAEDPYRKPPPFEKLIGDLAGAYSRRINIQHRLVYQVLEDEGVIKVL
RLWSHYE
Download Length: 264 bp
>T201800 NZ_CP098769:c4705473-4704940 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA
Antitoxin
Download Length: 81 a.a. Molecular weight: 9025.13 Da Isoelectric Point: 4.0066
>AT201800 WP_133732766.1 NZ_CP074200:c702991-702749 [Halomonas sp. FeN2]
MTGISATEARSNLYRLIDETAESHQPIVIMGKRNKAVLVAEEDWSAIQETLFLLSVPGMRESVRDGMETPVDECDEELDW
MTGISATEARSNLYRLIDETAESHQPIVIMGKRNKAVLVAEEDWSAIQETLFLLSVPGMRESVRDGMETPVDECDEELDW
Download Length: 243 bp
>AT201800 NZ_CP098769:c4705750-4705484 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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