Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-YefM
Location 702489..702991 Replicon chromosome
Accession NZ_CP074200
Organism Halomonas sp. FeN2

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag KF947_RS03320 Protein ID WP_133732765.1
Coordinates 702489..702752 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag KF947_RS03325 Protein ID WP_133732766.1
Coordinates 702749..702991 (-) Length 81 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KF947_RS03300 (KF947_03300) 698396..698719 + 324 WP_007113240.1 thioredoxin -
KF947_RS03305 (KF947_03305) 698790..699893 - 1104 WP_133732762.1 AI-2E family transporter -
KF947_RS03310 (KF947_03310) 700097..700954 + 858 WP_227405444.1 SIMPL domain-containing protein -
KF947_RS03315 (KF947_03315) 700899..702176 - 1278 WP_227405445.1 serine--tRNA ligase -
KF947_RS03320 (KF947_03320) 702489..702752 - 264 WP_133732765.1 Txe/YoeB family addiction module toxin Toxin
KF947_RS03325 (KF947_03325) 702749..702991 - 243 WP_133732766.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KF947_RS03330 (KF947_03330) 703339..704586 + 1248 WP_133732767.1 dicarboxylate/amino acid:cation symporter -
KF947_RS03335 (KF947_03335) 704742..705332 + 591 WP_227405446.1 DUF4202 domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(25-86)

Antitoxin

(1-69)


Sequences


Toxin        


Download         Length: 88 a.a.        Molecular weight: 10040.72 Da        Isoelectric Point: 10.0702

>T201800 WP_133732765.1 NZ_CP074200:c702752-702489 [Halomonas sp. FeN2]
VTWKLVYTKHAQKDAKKLASSGLKPKAQELLALIAEDPYRKPPPFEKLIGDLAGAYSRRINIQHRLVYQVLEDEGVIKVL
RLWSHYE

Download         Length: 264 bp

>T201800 NZ_CP098769:c4705473-4704940 [Klebsiella pneumoniae]
ATGGAGCAGCAACTGACGATTGAGATGATTGCCGATGCGTTCAGCTACGATATCACTGGATTTGATTGCGGCGAGGAAGC
GCTGAATACGTTTTTAAAAGAGCACCTCAAGCGGCAGCACGATGGACAAATCTTAAGGGGTTATGCGCTGGTCTCCGGGG
ATACCGTTCCCAGGTTGCTGGGTTATTACACCTTATCGGGGAGTTGTTTCGAGCGAGGCATGTTGCCGTCTAAAACTCAG
CAAAAGAAAATCCCGTATCAAAATGCGCCAAGCGTAACCCTCGGGCGGCTGGCCATTGATAAATCTGTTCAGGGGCAGGG
CTGGGGAGAGATGTTGGTTGCCCATGTGATGCGAGTGGTGTGGGGAGCGTCTAAAGCCGTTGGCATCTACGGATTGTTTG
TTGAAGCCCTTAATGAGAAAGCTAAAGCATTCTATCTTCGTCTGGGGTTTATACAGCTCGTGGATGAAAATAGTAACTTA
CTGTTTTATCCGACCAAATCGATTGAACAGCTCTTTACTGACGATGAGTCATAA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9025.13 Da        Isoelectric Point: 4.0066

>AT201800 WP_133732766.1 NZ_CP074200:c702991-702749 [Halomonas sp. FeN2]
MTGISATEARSNLYRLIDETAESHQPIVIMGKRNKAVLVAEEDWSAIQETLFLLSVPGMRESVRDGMETPVDECDEELDW

Download         Length: 243 bp

>AT201800 NZ_CP098769:c4705750-4705484 [Klebsiella pneumoniae]
ATGCCCGCACTTAAAAAGCAGCGTATAGATTTGAGATTAACCGATGATGATAAGAGCATCATCGAGGAAGCTGCGGCAAT
TTCGAATCAGACGATTACCCAGTTTGTGGTTGCCAGTGCCTCAGAACGTGCTGCGGAAGTGATTGAGCAGCACCGCAGAA
TGGTCCTCAATGAGCAATCATGGAGCCTGGTGATGGAGGCGATTACCCAACCGCCAGCCCCGAATGATCGACTGAAACGT
GCAGCGAAGCGTCTACAAACCAGGTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References