Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
Location | 4200487..4201147 | Replicon | chromosome |
Accession | NZ_CP074177 | ||
Organism | Enterobacter asburiae strain JBIWA002 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | KGP20_RS20655 | Protein ID | WP_223604394.1 |
Coordinates | 4200794..4201147 (-) | Length | 118 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | A0A1Z3MX79 |
Locus tag | KGP20_RS20650 | Protein ID | WP_029741460.1 |
Coordinates | 4200487..4200789 (-) | Length | 101 a.a. |
Genomic Context
Location: 4196447..4198636 (2190 bp)
Type: Others
Protein ID: WP_045356712.1
Type: Others
Protein ID: WP_045356712.1
Location: 4199491..4200411 (921 bp)
Type: Others
Protein ID: WP_223604393.1
Type: Others
Protein ID: WP_223604393.1
Location: 4202389..4202997 (609 bp)
Type: Others
Protein ID: WP_223604396.1
Type: Others
Protein ID: WP_223604396.1
Location: 4198960..4199349 (390 bp)
Type: Others
Protein ID: WP_223604392.1
Type: Others
Protein ID: WP_223604392.1
Location: 4200487..4200789 (303 bp)
Type: Antitoxin
Protein ID: WP_029741460.1
Type: Antitoxin
Protein ID: WP_029741460.1
Location: 4200794..4201147 (354 bp)
Type: Toxin
Protein ID: WP_223604394.1
Type: Toxin
Protein ID: WP_223604394.1
Location: 4201325..4202218 (894 bp)
Type: Others
Protein ID: WP_223604395.1
Type: Others
Protein ID: WP_223604395.1
Location: 4203041..4203991 (951 bp)
Type: Others
Protein ID: WP_223604397.1
Type: Others
Protein ID: WP_223604397.1
Location: 4204088..4205005 (918 bp)
Type: Others
Protein ID: WP_008499475.1
Type: Others
Protein ID: WP_008499475.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KGP20_RS20630 (KGP20_20545) | 4196447..4198636 | + | 2190 | WP_045356712.1 | TonB-dependent siderophore receptor | - |
KGP20_RS20640 (KGP20_20555) | 4198960..4199349 | - | 390 | WP_223604392.1 | RidA family protein | - |
KGP20_RS20645 (KGP20_20560) | 4199491..4200411 | + | 921 | WP_223604393.1 | LysR family transcriptional regulator | - |
KGP20_RS20650 (KGP20_20565) | 4200487..4200789 | - | 303 | WP_029741460.1 | XRE family transcriptional regulator | Antitoxin |
KGP20_RS20655 (KGP20_20570) | 4200794..4201147 | - | 354 | WP_223604394.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
KGP20_RS20660 (KGP20_20575) | 4201325..4202218 | - | 894 | WP_223604395.1 | LysR substrate-binding domain-containing protein | - |
KGP20_RS20665 (KGP20_20580) | 4202389..4202997 | + | 609 | WP_223604396.1 | glutathione S-transferase family protein | - |
KGP20_RS20670 (KGP20_20585) | 4203041..4203991 | - | 951 | WP_223604397.1 | HTH-type transcriptional regulator Cbl | - |
KGP20_RS20675 (KGP20_20590) | 4204088..4205005 | - | 918 | WP_008499475.1 | nitrogen assimilation transcriptional regulator NAC | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
No matching records found |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 118 a.a. Molecular weight: 13547.40 Da Isoelectric Point: 9.0310
>T201777 WP_223604394.1 NZ_CP074177:c4201147-4200794 [Enterobacter asburiae]
VWAINTTDRFDRWFTSLDDTERASVLAALLVLREKGLGLSRPYADTLKGSRHSNMKELRIQSKGDPLRAFFAFDPNRTGI
VLCAGNKVGNERRFYDEMLLVADREFTHWLNTLKERE
VWAINTTDRFDRWFTSLDDTERASVLAALLVLREKGLGLSRPYADTLKGSRHSNMKELRIQSKGDPLRAFFAFDPNRTGI
VLCAGNKVGNERRFYDEMLLVADREFTHWLNTLKERE
Download Length: 354 bp
>T201777 NZ_CP098757:c5535427-5535011 [Klebsiella oxytoca]
GTGATCAAAACCTATATGCTGGACACCAACATTTGCTCATTTATCATGCGTGAGCAACCGGAAGCTGTCATCAAACGGCT
AGAACAGGCAGTACTGCGTAATCACCGCATCGTGGTTTCGGCCATCACCTATGCCGAGATGCGTTTCGGTGCGATCGGAA
AGAAGGCATCCCCCCGCCACGGCCTGCTTGTCGAAGCTTTCTGCGCCCGCCTCGATGCAATCCTCGCCTGGGACCGCGCC
GCGGTGGACGCAACCACGGAGATTAAGGCCGCACTGACTGCGGCCGGGACGCCAATTGGTCCGAACGACACGGCAATTGC
CGGGCATGCTATCGCCGCCGGCGCCGTACTGGTGACGAACAACGTGCGAGAGTTTGAGCGTGTGCCTGGACTAATTCTGG
AAGACTGGGCTAACTGA
GTGATCAAAACCTATATGCTGGACACCAACATTTGCTCATTTATCATGCGTGAGCAACCGGAAGCTGTCATCAAACGGCT
AGAACAGGCAGTACTGCGTAATCACCGCATCGTGGTTTCGGCCATCACCTATGCCGAGATGCGTTTCGGTGCGATCGGAA
AGAAGGCATCCCCCCGCCACGGCCTGCTTGTCGAAGCTTTCTGCGCCCGCCTCGATGCAATCCTCGCCTGGGACCGCGCC
GCGGTGGACGCAACCACGGAGATTAAGGCCGCACTGACTGCGGCCGGGACGCCAATTGGTCCGAACGACACGGCAATTGC
CGGGCATGCTATCGCCGCCGGCGCCGTACTGGTGACGAACAACGTGCGAGAGTTTGAGCGTGTGCCTGGACTAATTCTGG
AAGACTGGGCTAACTGA
Antitoxin
Download Length: 101 a.a. Molecular weight: 11050.83 Da Isoelectric Point: 5.7316
>AT201777 WP_029741460.1 NZ_CP074177:c4200789-4200487 [Enterobacter asburiae]
MGRTLEQLIADEKPEVVASAQAIATDILLNIHLAELREKVQKTQVEMAQALGIRQPTVAVMEKPGRDLKLSSLKRYVEAA
GGKLRLDVELPDGSHYEFVL
MGRTLEQLIADEKPEVVASAQAIATDILLNIHLAELREKVQKTQVEMAQALGIRQPTVAVMEKPGRDLKLSSLKRYVEAA
GGKLRLDVELPDGSHYEFVL
Download Length: 303 bp
>AT201777 NZ_CP098757:c5535654-5535424 [Klebsiella oxytoca]
ATGAGAACCGTATCGATATTTAAAAACGGCAATAATCGTGCTATCCGTCTGCCCCGAGACCTGGATTTTGAGGGAGTGAG
CGAACTGGAAATCGTCCGGGAAGGTGACAGCATCATCCTTCGTCCCGTTCGACCAACATGGGGTTCGTTTACTCAGCTCG
AAAAAGCCGATTCAGACTTTATGGCCGAGCGTGGTGACATTGTCAGCGATGAAGGACGATTTGACCTGTGA
ATGAGAACCGTATCGATATTTAAAAACGGCAATAATCGTGCTATCCGTCTGCCCCGAGACCTGGATTTTGAGGGAGTGAG
CGAACTGGAAATCGTCCGGGAAGGTGACAGCATCATCCTTCGTCCCGTTCGACCAACATGGGGTTCGTTTACTCAGCTCG
AAAAAGCCGATTCAGACTTTATGGCCGAGCGTGGTGACATTGTCAGCGATGAAGGACGATTTGACCTGTGA
Structures
Toxin
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Source | ID | Structure |
---|---|---|
No matching records found |
Antitoxin
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Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1Z3MX79 |