Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/COG4683-HTH_37 |
Location | 1704313..1704967 | Replicon | chromosome |
Accession | NZ_CP074112 | ||
Organism | Idiomarina loihiensis strain SN11 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | KGF88_RS08175 | Protein ID | WP_110076065.1 |
Coordinates | 1704313..1704672 (+) | Length | 120 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | KGF88_RS08180 | Protein ID | WP_110076064.1 |
Coordinates | 1704665..1704967 (+) | Length | 101 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KGF88_RS08160 (KGF88_08185) | 1699958..1700602 | - | 645 | WP_153825959.1 | response regulator transcription factor | - |
KGF88_RS08165 (KGF88_08190) | 1700695..1702638 | - | 1944 | WP_153825960.1 | acetate--CoA ligase | - |
KGF88_RS08170 (KGF88_08195) | 1703011..1704189 | + | 1179 | WP_153825961.1 | DcaP family trimeric outer membrane transporter | - |
KGF88_RS08175 (KGF88_08200) | 1704313..1704672 | + | 360 | WP_110076065.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
KGF88_RS08180 (KGF88_08205) | 1704665..1704967 | + | 303 | WP_110076064.1 | helix-turn-helix transcriptional regulator | Antitoxin |
KGF88_RS08185 (KGF88_08210) | 1705042..1705629 | - | 588 | WP_110076063.1 | hypothetical protein | - |
KGF88_RS08190 (KGF88_08215) | 1705626..1706837 | - | 1212 | WP_162014454.1 | transglycosylase SLT domain-containing protein | - |
KGF88_RS08195 (KGF88_08220) | 1706791..1707519 | - | 729 | WP_153825963.1 | hypothetical protein | - |
KGF88_RS08200 (KGF88_08225) | 1707519..1708790 | - | 1272 | WP_162014455.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 120 a.a. Molecular weight: 13627.56 Da Isoelectric Point: 7.8823
>T201468 WP_110076065.1 NZ_CP074112:1704313-1704672 [Idiomarina loihiensis]
MWTIRTTDRFDAWFDALDDTDKENVIASLLLLQSEGPFLSRPYADTLYGSVHSNLKELRIQSKGKPIRVCFAFDLSRTAI
ILCAAHKNRNTRLFYQTMIATADQEFTRHLIAMGQKDNG
MWTIRTTDRFDAWFDALDDTDKENVIASLLLLQSEGPFLSRPYADTLYGSVHSNLKELRIQSKGKPIRVCFAFDLSRTAI
ILCAAHKNRNTRLFYQTMIATADQEFTRHLIAMGQKDNG
Download Length: 360 bp
>T201468 NZ_CP098439:98228-98533 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTACAGAGTGATATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGCTGTCAGATAAAGTCTCCCGTGAACTTTACCCGGTGG
TGCATATCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGCCACCGCGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTACAGAGTGATATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGCTGTCAGATAAAGTCTCCCGTGAACTTTACCCGGTGG
TGCATATCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGCCACCGCGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA
Antitoxin
Download Length: 101 a.a. Molecular weight: 10982.88 Da Isoelectric Point: 9.6858
>AT201468 WP_110076064.1 NZ_CP074112:1704665-1704967 [Idiomarina loihiensis]
MARTLEQLIANEKPELIARASKKADAMLLTIRLSEIRKLVNKTQVDLANSMGIKQPTVAGMEKTGADIKLSSLKKYIEAC
GAHLKVDIELPDGSHHQFSL
MARTLEQLIANEKPELIARASKKADAMLLTIRLSEIRKLVNKTQVDLANSMGIKQPTVAGMEKTGADIKLSSLKKYIEAC
GAHLKVDIELPDGSHHQFSL
Download Length: 303 bp
>AT201468 NZ_CP098439:98008-98226 [Salmonella enterica subsp. enterica serovar Typhimurium]
ATGAAGCAGCGTATTACAGTGACAGTTGACAGCGACAGCTATCAGTTGCTCAAGGCATATGATGTCAATATCTCCGGTCT
GGTAAGCACAACCATGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGAAAGCGGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCTGACGAGAACAGGGACTGGTGA
ATGAAGCAGCGTATTACAGTGACAGTTGACAGCGACAGCTATCAGTTGCTCAAGGCATATGATGTCAATATCTCCGGTCT
GGTAAGCACAACCATGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGAAAGCGGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCTGACGAGAACAGGGACTGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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