20107

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5190100..5190704 Replicon chromosome
Accession LT629788
Organism Pseudomonas moraviensis strain BS3668

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag SAMN04490196_4867 Protein ID SDU72528.1
Coordinates 5190390..5190704 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag SAMN04490196_4866 Protein ID SDU72521.1
Coordinates 5190100..5190387 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAMN04490196_4862 5185876..5186280 + 405 SDU72496.1 heat shock protein Hsp15 -
SAMN04490196_4863 5186439..5187242 - 804 SDU72502.1 PAP2 superfamily protein -
SAMN04490196_4864 5187349..5188251 + 903 SDU72509.1 molecular chaperone Hsp33 -
SAMN04490196_4865 5188433..5189974 + 1542 SDU72515.1 phosphoenolpyruvate carboxykinase (ATP) -
SAMN04490196_4866 5190100..5190387 - 288 SDU72521.1 transcriptional regulator, XRE family Antitoxin
SAMN04490196_4867 5190390..5190704 - 315 SDU72528.1 RelE toxin of RelE / RelB toxin-antitoxin system Toxin
SAMN04490196_4868 5190810..5191109 - 300 SDU72534.1 hypothetical protein -
SAMN04490196_4870 5191455..5192597 - 1143 SDU72541.1 hypothetical protein -
SAMN04490196_4871 5192896..5194830 + 1935 SDU72547.1 ATP-dependent DNA helicase, RecQ-like -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(43-100)

Antitoxin

Cro/C1-type helix-turn-helix domain

(36-73)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11713.42 Da        Isoelectric Point: 10.0567

>T20107 SDU72528.1 LT629788:c5190704-5190390 [Pseudomonas moraviensis]
MIFIETSVFTRRVRELLDDDAYATFQKQLVADPSIGDVIEGTGGVRKARVASKGHGKRGGARVIYYHFVSASQIALLMIY
SKNEQQDLTHDERKALKAMIGNWR

Download         Length: 315 bp

>T20107 LT629788:c5190704-5190390 [Pseudomonas moraviensis]
ATGATTTTTATTGAGACTTCAGTCTTTACCCGCCGAGTAAGAGAGTTACTGGACGACGATGCCTACGCCACCTTTCAAAA
GCAGCTGGTCGCAGACCCGTCCATTGGCGATGTAATCGAAGGGACCGGGGGGGTGCGTAAAGCACGAGTCGCCTCCAAAG
GCCACGGTAAACGAGGAGGAGCACGGGTCATCTACTACCACTTCGTTTCAGCATCACAGATCGCGTTGTTGATGATTTAC
TCAAAAAATGAGCAGCAGGATCTTACTCATGACGAACGGAAAGCACTGAAGGCCATGATTGGAAACTGGAGGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10727.38 Da        Isoelectric Point: 8.7453

>AT20107 SDU72521.1 LT629788:c5190387-5190100 [Pseudomonas moraviensis]
MSKFFDELMESVQEMDEILRGEKKPSREFHVDALQVKQIRKATGMTQAKFAALIDVQLGTLRNWEQGRRQPTGPAKALLK
AIHNDPVHVLSALAD

Download         Length: 288 bp

>AT20107 LT629788:c5190387-5190100 [Pseudomonas moraviensis]
ATGAGCAAATTTTTTGATGAGCTGATGGAAAGCGTGCAGGAAATGGATGAGATTCTTCGGGGTGAAAAAAAACCTTCCCG
CGAATTTCATGTGGATGCATTACAGGTTAAACAGATTCGCAAAGCGACGGGAATGACGCAGGCAAAGTTCGCAGCCTTGA
TTGATGTCCAGCTCGGGACGTTACGCAATTGGGAGCAAGGTCGTCGTCAGCCGACTGGCCCGGCTAAAGCATTGCTCAAG
GCCATTCATAACGATCCTGTCCATGTGCTCAGTGCACTTGCTGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References