20104

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4053908..4054512 Replicon chromosome
Accession LT629788
Organism Pseudomonas moraviensis strain BS3668

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag SAMN04490196_3780 Protein ID SDU62270.1
Coordinates 4053908..4054210 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag SAMN04490196_3781 Protein ID SDU62280.1
Coordinates 4054225..4054512 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
SAMN04490196_3776 4049508..4049675 - 168 SDU62222.1 Protein of unknown function -
SAMN04490196_3777 4049760..4050767 - 1008 SDU62233.1 cytochrome bd-I ubiquinol oxidase subunit 2 apoprotein -
SAMN04490196_3778 4050771..4052216 - 1446 SDU62244.1 cytochrome bd-I ubiquinol oxidase subunit 1 apoprotein -
SAMN04490196_3779 4052597..4053832 + 1236 SDU62258.1 Predicted arabinose efflux permease, MFS family -
SAMN04490196_3780 4053908..4054210 + 303 SDU62270.1 proteic killer suppression protein Toxin
SAMN04490196_3781 4054225..4054512 + 288 SDU62280.1 addiction module antidote protein, HigA family Antitoxin
SAMN04490196_3782 4054526..4055068 - 543 SDU62293.1 4-methyl-5(b-hydroxyethyl)-thiazole monophosphate biosynthesis -
SAMN04490196_3783 4055135..4055581 - 447 SDU62306.1 protein of unknown function -
SAMN04490196_3784 4055802..4057097 + 1296 SDU62316.1 putative MFS transporter, AGZA family, xanthine/uracil permease -
SAMN04490196_3785 4057094..4058173 + 1080 SDU62327.1 tRNA (uracil-5-)-methyltransferase -
SAMN04490196_3786 4058228..4058674 - 447 SDU62338.1 Protein of unknown function -
SAMN04490196_3787 4058671..4059099 - 429 SDU62350.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(9-100)

Antitoxin

Cro/C1-type helix-turn-helix domain

(20-75)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11691.48 Da        Isoelectric Point: 9.7863

>T20104 SDU62270.1 LT629788:4053908-4054210 [Pseudomonas moraviensis]
MYRLTLAAMIKSFQHKGLRGFYETGTTRGIRAEHAKRLSRMLQFMDRATLPGDLDLPGWRLHPLKGELSEYWSLSVSGNW
RVIFRFVGSDIELVDYLDYH

Download         Length: 303 bp

>T20104 LT629788:4053908-4054210 [Pseudomonas moraviensis]
ATGTATCGCCTTACACTCGCCGCCATGATCAAATCCTTTCAGCACAAAGGCCTTCGTGGCTTCTATGAAACAGGTACGAC
TCGTGGAATTCGTGCCGAGCATGCAAAACGGCTGTCGCGCATGTTGCAGTTCATGGATCGAGCGACGCTTCCCGGGGACT
TGGACTTGCCCGGCTGGCGCCTGCATCCTTTGAAAGGTGAGCTAAGCGAATATTGGTCGCTCAGCGTTTCAGGCAACTGG
CGAGTGATCTTTCGTTTTGTCGGTTCGGATATCGAATTGGTCGATTATCTGGACTACCACTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10525.13 Da        Isoelectric Point: 6.6962

>AT20104 SDU62280.1 LT629788:4054225-4054512 [Pseudomonas moraviensis]
MPMHNPPHPGETLLLDVLPELGISVSELARHLGFARPHLSRVLHGHAPISPDLAVRLERAGIGKARVWLGVQTDYDLWQA
EHREQPMIEPLAAHG

Download         Length: 288 bp

>AT20104 LT629788:4054225-4054512 [Pseudomonas moraviensis]
ATGCCCATGCACAACCCGCCACACCCCGGTGAAACCCTGCTGCTGGATGTCTTGCCCGAGCTTGGCATCAGCGTGAGCGA
ATTAGCCCGGCACCTTGGCTTTGCACGCCCGCACCTTTCGCGCGTACTGCACGGACACGCGCCAATCAGCCCGGATCTGG
CAGTACGACTTGAGCGTGCAGGGATCGGCAAGGCGCGCGTTTGGCTAGGCGTCCAAACCGACTACGATCTTTGGCAAGCG
GAGCACCGTGAGCAACCAATGATAGAACCCCTCGCAGCCCACGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References