Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 3599036..3599851 Replicon chromosome
Accession NZ_CP073914
Organism Proteus terrae subsp. cibarius strain SH19PTE4

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag KF949_RS17010 Protein ID WP_211838660.1
Coordinates 3599378..3599851 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag KF949_RS17005 Protein ID WP_075673430.1
Coordinates 3599036..3599371 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KF949_RS16985 (KF949_16985) 3594726..3596150 + 1425 WP_072069056.1 aspartate ammonia-lyase -
KF949_RS16990 (KF949_16990) 3596309..3597634 + 1326 WP_036934359.1 anaerobic C4-dicarboxylate transporter -
KF949_RS16995 (KF949_16995) 3597818..3598390 + 573 WP_075673431.1 transcriptional regulator -
KF949_RS17005 (KF949_17005) 3599036..3599371 + 336 WP_075673430.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
KF949_RS17010 (KF949_17010) 3599378..3599851 + 474 WP_211838660.1 type II toxin-antitoxin system YhaV family toxin Toxin
KF949_RS17015 (KF949_17015) 3600165..3600812 + 648 WP_075673428.1 type II CAAX endopeptidase family protein -
KF949_RS17020 (KF949_17020) 3601115..3601750 + 636 WP_075673427.1 DUF1449 family protein -
KF949_RS17025 (KF949_17025) 3601837..3604032 + 2196 WP_099659727.1 flotillin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-147)

Antitoxin

PrlF antitoxin

(15-109)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 18651.31 Da        Isoelectric Point: 9.2715

>T200532 WP_211838660.1 NZ_CP073914:3599378-3599851 [Proteus terrae subsp. cibarius]
MDFPTDLNGWTIYAHPCFKQQYDELLQKVEALKKKYPEDYQKKADIKIFAHVLKSIVNITNDPRAPEFRLGNTLGEENKN
WSRIKLVNGRYRLFFRFSFKEKIIILAWINDNDTLRTYGNKTDAYRVFEKKLKKGHPPKNWNDLFSDCINEADCQDP

Download         Length: 474 bp

>T200532 NZ_CP097884:3223740-3223847 [Escherichia coli str. K-12 substr. MG1655]
ATGACGCTCGCGCAGTTTGCCATGACTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12312.67 Da        Isoelectric Point: 4.2560

>AT200532 WP_075673430.1 NZ_CP073914:3599036-3599371 [Proteus terrae subsp. cibarius]
MLTHVCTDNIALEADSKITERHQTTIPASIREALHLSGGDRIHYKLLSTGDVLISRHSDGSEDPVMASFLNFLAQDITNH
PQTIQPLDISRGFELVEGMDINLDDDITDNE

Download         Length: 336 bp

>AT200532 NZ_CP097884:c3223693-3223627 [Escherichia coli str. K-12 substr. MG1655]
TGTCTGGTTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References