Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | prlF-yhaV (relBE)/YhaV-PrlF |
Location | 1087176..1087991 | Replicon | chromosome |
Accession | NZ_CP073630 | ||
Organism | Proteus terrae subsp. cibarius strain S24-2-1 |
Toxin (Protein)
Gene name | yhaV | Uniprot ID | - |
Locus tag | KEF19_RS05030 | Protein ID | WP_075673429.1 |
Coordinates | 1087176..1087649 (-) | Length | 158 a.a. |
Antitoxin (Protein)
Gene name | prlF | Uniprot ID | - |
Locus tag | KEF19_RS05035 | Protein ID | WP_075673430.1 |
Coordinates | 1087656..1087991 (-) | Length | 112 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
KEF19_RS05015 | 1082998..1085193 | - | 2196 | WP_099659727.1 | flotillin family protein | - |
KEF19_RS05020 | 1085280..1085915 | - | 636 | WP_156734149.1 | DUF1449 family protein | - |
KEF19_RS05025 | 1086218..1086865 | - | 648 | WP_075673428.1 | type II CAAX endopeptidase family protein | - |
KEF19_RS05030 | 1087176..1087649 | - | 474 | WP_075673429.1 | type II toxin-antitoxin system YhaV family toxin | Toxin |
KEF19_RS05035 | 1087656..1087991 | - | 336 | WP_075673430.1 | type II toxin-antitoxin system PrlF family antitoxin | Antitoxin |
KEF19_RS05045 | 1088638..1089210 | - | 573 | WP_075673431.1 | transcriptional regulator | - |
KEF19_RS05050 | 1089394..1090719 | - | 1326 | WP_036934359.1 | anaerobic C4-dicarboxylate transporter | - |
KEF19_RS05055 | 1090878..1092302 | - | 1425 | WP_072069056.1 | aspartate ammonia-lyase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
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Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 158 a.a. Molecular weight: 18639.26 Da Isoelectric Point: 9.2715
>T199956 WP_075673429.1 NZ_CP073630:c1087649-1087176 [Proteus terrae subsp. cibarius]
MDFPTDLNGWTIYAHPCFKQQYDELLQKVEALKKKYPEDYQKKADTKIFAHVLKSIVNITNDPRAPEFRLGNTLGEENKN
WSRIKLVNGRYRLFFRFSFKEKIIILAWINDNDTLRTYGNKTDAYRVFEKKLKKGHPPKNWNDLFSDCINEADCQDP
MDFPTDLNGWTIYAHPCFKQQYDELLQKVEALKKKYPEDYQKKADTKIFAHVLKSIVNITNDPRAPEFRLGNTLGEENKN
WSRIKLVNGRYRLFFRFSFKEKIIILAWINDNDTLRTYGNKTDAYRVFEKKLKKGHPPKNWNDLFSDCINEADCQDP
Download Length: 474 bp
>T199956 NZ_CP097668:c197969-197553 [Klebsiella pneumoniae]
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAGCCTGAAGCAGTGCTTAAGAATCT
GGAGCAGGCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGCGCCACCGGTC
CAAAGGCATCGCCACGCCACGTGCAGCTGGTTGACGCGTTCTGCGCCCGTCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGATGCAACCACGGAGGTTAAGGTGGCGCTGCGCCTCGCCGGCACGCCGATCGGTCCAAACGACACGGCGATCGC
CGGGCACGCCATCGCCACCGGGGCAATACTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTGCCTGGACTGGTACTGG
AAGACTGGGCAGGATAA
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAGCCTGAAGCAGTGCTTAAGAATCT
GGAGCAGGCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGCGCCACCGGTC
CAAAGGCATCGCCACGCCACGTGCAGCTGGTTGACGCGTTCTGCGCCCGTCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGATGCAACCACGGAGGTTAAGGTGGCGCTGCGCCTCGCCGGCACGCCGATCGGTCCAAACGACACGGCGATCGC
CGGGCACGCCATCGCCACCGGGGCAATACTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTGCCTGGACTGGTACTGG
AAGACTGGGCAGGATAA
Antitoxin
Download Length: 112 a.a. Molecular weight: 12312.67 Da Isoelectric Point: 4.2560
>AT199956 WP_075673430.1 NZ_CP073630:c1087991-1087656 [Proteus terrae subsp. cibarius]
MLTHVCTDNIALEADSKITERHQTTIPASIREALHLSGGDRIHYKLLSTGDVLISRHSDGSEDPVMASFLNFLAQDITNH
PQTIQPLDISRGFELVEGMDINLDDDITDNE
MLTHVCTDNIALEADSKITERHQTTIPASIREALHLSGGDRIHYKLLSTGDVLISRHSDGSEDPVMASFLNFLAQDITNH
PQTIQPLDISRGFELVEGMDINLDDDITDNE
Download Length: 336 bp
>AT199956 NZ_CP097668:c198196-197966 [Klebsiella pneumoniae]
ATGAGAACCGTATCTATTTTCAAAAATGGCAATAACCGCGCGATCCGTCTGCCCCGCGATCTGGATTTTGAGGGGGTGAG
TGAGCTGGAGATTGTACGGGAAGGGGACAGAATCATTCTGCGTCCCCTCCGCCCGAGCTGGAGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGGCTTTATGACGGAACGCGAGGACGTTGTCTGCGACGAAGGACGATTTAACCTGTGA
ATGAGAACCGTATCTATTTTCAAAAATGGCAATAACCGCGCGATCCGTCTGCCCCGCGATCTGGATTTTGAGGGGGTGAG
TGAGCTGGAGATTGTACGGGAAGGGGACAGAATCATTCTGCGTCCCCTCCGCCCGAGCTGGAGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGGCTTTATGACGGAACGCGAGGACGTTGTCTGCGACGAAGGACGATTTAACCTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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