Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 1087176..1087991 Replicon chromosome
Accession NZ_CP073630
Organism Proteus terrae subsp. cibarius strain S24-2-1

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag KEF19_RS05030 Protein ID WP_075673429.1
Coordinates 1087176..1087649 (-) Length 158 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag KEF19_RS05035 Protein ID WP_075673430.1
Coordinates 1087656..1087991 (-) Length 112 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KEF19_RS05015 1082998..1085193 - 2196 WP_099659727.1 flotillin family protein -
KEF19_RS05020 1085280..1085915 - 636 WP_156734149.1 DUF1449 family protein -
KEF19_RS05025 1086218..1086865 - 648 WP_075673428.1 type II CAAX endopeptidase family protein -
KEF19_RS05030 1087176..1087649 - 474 WP_075673429.1 type II toxin-antitoxin system YhaV family toxin Toxin
KEF19_RS05035 1087656..1087991 - 336 WP_075673430.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
KEF19_RS05045 1088638..1089210 - 573 WP_075673431.1 transcriptional regulator -
KEF19_RS05050 1089394..1090719 - 1326 WP_036934359.1 anaerobic C4-dicarboxylate transporter -
KEF19_RS05055 1090878..1092302 - 1425 WP_072069056.1 aspartate ammonia-lyase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(12-147)

Antitoxin

(15-109)


Sequences


Toxin        


Download         Length: 158 a.a.        Molecular weight: 18639.26 Da        Isoelectric Point: 9.2715

>T199956 WP_075673429.1 NZ_CP073630:c1087649-1087176 [Proteus terrae subsp. cibarius]
MDFPTDLNGWTIYAHPCFKQQYDELLQKVEALKKKYPEDYQKKADTKIFAHVLKSIVNITNDPRAPEFRLGNTLGEENKN
WSRIKLVNGRYRLFFRFSFKEKIIILAWINDNDTLRTYGNKTDAYRVFEKKLKKGHPPKNWNDLFSDCINEADCQDP

Download         Length: 474 bp

>T199956 NZ_CP097668:c197969-197553 [Klebsiella pneumoniae]
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAGCCTGAAGCAGTGCTTAAGAATCT
GGAGCAGGCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGCGCCACCGGTC
CAAAGGCATCGCCACGCCACGTGCAGCTGGTTGACGCGTTCTGCGCCCGTCTCGATGCCATCCTGCCCTGGGATCGCGCT
GCGGTGGATGCAACCACGGAGGTTAAGGTGGCGCTGCGCCTCGCCGGCACGCCGATCGGTCCAAACGACACGGCGATCGC
CGGGCACGCCATCGCCACCGGGGCAATACTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTGCCTGGACTGGTACTGG
AAGACTGGGCAGGATAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12312.67 Da        Isoelectric Point: 4.2560

>AT199956 WP_075673430.1 NZ_CP073630:c1087991-1087656 [Proteus terrae subsp. cibarius]
MLTHVCTDNIALEADSKITERHQTTIPASIREALHLSGGDRIHYKLLSTGDVLISRHSDGSEDPVMASFLNFLAQDITNH
PQTIQPLDISRGFELVEGMDINLDDDITDNE

Download         Length: 336 bp

>AT199956 NZ_CP097668:c198196-197966 [Klebsiella pneumoniae]
ATGAGAACCGTATCTATTTTCAAAAATGGCAATAACCGCGCGATCCGTCTGCCCCGCGATCTGGATTTTGAGGGGGTGAG
TGAGCTGGAGATTGTACGGGAAGGGGACAGAATCATTCTGCGTCCCCTCCGCCCGAGCTGGAGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGGCTTTATGACGGAACGCGAGGACGTTGTCTGCGACGAAGGACGATTTAACCTGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References