Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 3391012..3391827 Replicon chromosome
Accession NZ_CP073356
Organism Proteus terrae subsp. cibarius strain SDQ8C180-2T

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag KDN45_RS15555 Protein ID WP_075673429.1
Coordinates 3391354..3391827 (+) Length 158 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag KDN45_RS15550 Protein ID WP_075673430.1
Coordinates 3391012..3391347 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KDN45_RS15530 (KDN45_15450) 3386701..3388125 + 1425 WP_072069056.1 aspartate ammonia-lyase -
KDN45_RS15535 (KDN45_15455) 3388284..3389609 + 1326 WP_036934359.1 anaerobic C4-dicarboxylate transporter -
KDN45_RS15540 (KDN45_15460) 3389793..3390365 + 573 WP_075673431.1 transcriptional regulator -
KDN45_RS15550 (KDN45_15470) 3391012..3391347 + 336 WP_075673430.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
KDN45_RS15555 (KDN45_15475) 3391354..3391827 + 474 WP_075673429.1 type II toxin-antitoxin system YhaV family toxin Toxin
KDN45_RS15560 3392138..3392392 + 255 WP_223673974.1 hypothetical protein -
KDN45_RS15565 3392365..3392784 + 420 WP_223673973.1 CPBP family intramembrane metalloprotease -
KDN45_RS15570 (KDN45_15485) 3393087..3393722 + 636 WP_223673972.1 DUF1449 family protein -
KDN45_RS15575 (KDN45_15490) 3393809..3396004 + 2196 WP_099659727.1 flotillin family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-147)

Antitoxin

PrlF antitoxin

(15-109)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 18639.26 Da        Isoelectric Point: 9.2715

>T199744 WP_075673429.1 NZ_CP073356:3391354-3391827 [Proteus terrae subsp. cibarius]
MDFPTDLNGWTIYAHPCFKQQYDELLQKVEALKKKYPEDYQKKADTKIFAHVLKSIVNITNDPRAPEFRLGNTLGEENKN
WSRIKLVNGRYRLFFRFSFKEKIIILAWINDNDTLRTYGNKTDAYRVFEKKLKKGHPPKNWNDLFSDCINEADCQDP

Download         Length: 474 bp

>T199744 NZ_CP097556:c5321050-5320772 [Pseudomonas aeruginosa]
GTGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCTTCATGCGGCTACGGAGCTTCGAGACTTGCGCTCTCCACCTGGAAACCGGTTGG
AGCCGTTGCAGGGAAAGCGGGCGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12312.67 Da        Isoelectric Point: 4.2560

>AT199744 WP_075673430.1 NZ_CP073356:3391012-3391347 [Proteus terrae subsp. cibarius]
MLTHVCTDNIALEADSKITERHQTTIPASIREALHLSGGDRIHYKLLSTGDVLISRHSDGSEDPVMASFLNFLAQDITNH
PQTIQPLDISRGFELVEGMDINLDDDITDNE

Download         Length: 336 bp

>AT199744 NZ_CP097556:c5320760-5320455 [Pseudomonas aeruginosa]
ATGGCTACCAATGGTATGCGCCCCATCCATCCTGGGGAAATATTGCGCGATGAGTTTCTGATGGAGTTGGATATCTCTCC
AGCTGCTCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAACGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTACTCGTTAGCA
ACTGCTTATGCGGCGAATGGCGAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCACGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References