199717

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 3611115..3611617 Replicon chromosome
Accession NZ_CP073343
Organism Marinomonas rhizomae strain MB12-11

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag KDW99_RS16990 Protein ID WP_255826351.1
Coordinates 3611115..3611378 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag KDW99_RS16995 Protein ID WP_255826352.1
Coordinates 3611375..3611617 (-) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KDW99_RS16965 (KDW99_16925) 3606247..3607500 - 1254 WP_255826346.1 D-amino acid dehydrogenase -
KDW99_RS16970 (KDW99_16930) 3607697..3608152 + 456 WP_255826347.1 regulatory protein RecX -
KDW99_RS16975 (KDW99_16935) 3608225..3609805 - 1581 WP_255826348.1 hypothetical protein -
KDW99_RS16980 (KDW99_16940) 3610016..3610168 + 153 Protein_3305 transposase domain-containing protein -
KDW99_RS16985 (KDW99_16945) 3610455..3611042 - 588 WP_255826350.1 alpha/beta hydrolase -
KDW99_RS16990 (KDW99_16950) 3611115..3611378 - 264 WP_255826351.1 Txe/YoeB family addiction module toxin Toxin
KDW99_RS16995 (KDW99_16955) 3611375..3611617 - 243 WP_255826352.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
KDW99_RS17000 (KDW99_16960) 3612600..3613430 - 831 WP_255826354.1 S-formylglutathione hydrolase -
KDW99_RS17005 (KDW99_16965) 3613523..3614641 - 1119 WP_255826355.1 S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase -
KDW99_RS17010 (KDW99_16970) 3614833..3615723 + 891 WP_255826357.1 LysR family transcriptional regulator -
KDW99_RS17015 (KDW99_16975) 3615783..3616046 + 264 WP_255826359.1 DUF3820 family protein -
KDW99_RS17020 (KDW99_16980) 3616073..3616537 - 465 WP_255826361.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(4-69)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10103.93 Da        Isoelectric Point: 10.4236

>T199717 WP_255826351.1 NZ_CP073343:c3611378-3611115 [Marinomonas rhizomae]
VTWKLIYTKQAQKDAKKLASIGLKPKAQELLSLVAQDPFQKPPPFEKLVGDLSGAYSRRINIQHRLVYQVLEAEKMIKVL
RLWTHYE

Download         Length: 264 bp

>T199717 NZ_CP097529:2846808-2847101 [Pseudomonas putida]
GTGCCACGACTGATCGTCACTGAAGGCGCGGCGAAGGGCCTGGAGCGTTGCCGGCGATTTCTCTCCGATAAAGATCCGCA
GGTCGCACGCCGTGCTGCACAGGCAATCGAGCGCCAATTCGCTCGATTGGAGGAAAGTCCGGAAGTAGGGCGTCCTTTTC
CAGATCTGCCAGAGCTGCGTGAGCTCATCATCGAGTTTGGTGACTCAGGTTACGTCGCGCTGTACCGCTATGAGCGCGCA
GATGACACCGCCTATGTCTTGGCCTTTCGCCATCAAAAAGAAGCTGGCTACTGA

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9000.00 Da        Isoelectric Point: 3.9487

>AT199717 WP_255826352.1 NZ_CP073343:c3611617-3611375 [Marinomonas rhizomae]
MAGMTATEARSNLYRLIDETADSHQPIVITGKRNNAVLVSEEDWSAIQETLFLLSVPNMRESIREGMDTPASECDEELDW

Download         Length: 243 bp

>AT199717 NZ_CP097529:2846548-2846820 [Pseudomonas putida]
ATGGCCACTTCCATCAAAATTGACGACGATCTGAAAGGTCGCATTCAGCATTTGGCTTGTTTGCGCCAGCGCTCATCTCA
CTGGATCATGCGTGAGGCGATCACCCAGTACGTCGAGCGTGAGGAGGCCCGTGAGAGCTTCAAACAAGAAGCGCTGGCAT
CTTGGGCTGCATACCAGGAAACCGGCCAGCACTTGACCGGCCAGGAGGCTCGCACCTGGCTTGGTAGTTGGGGTACAGAT
GCTGAGGCAGAGTTACCCAAGTGCCACGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References