199528

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /PIN(toxin)
Location 9713..10373 Replicon plasmid pSYSG
Accession NZ_CP073021
Organism Synechocystis sp. PCC 6803

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag KBZ93_RS18265 Protein ID WP_011153785.1
Coordinates 9948..10373 (+) Length 142 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag KBZ93_RS18260 Protein ID WP_011153784.1
Coordinates 9713..9940 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KBZ93_RS18235 (KBZ93_18240) 6043..6393 - 351 WP_011153778.1 DUF5615 family PIN-like protein -
KBZ93_RS18240 (KBZ93_18245) 6377..6601 - 225 WP_011153779.1 DUF433 domain-containing protein -
KBZ93_RS18245 (KBZ93_18250) 6652..8619 - 1968 Protein_9 type I restriction-modification system subunit M -
KBZ93_RS18250 (KBZ93_18255) 8821..9195 - 375 WP_011153782.1 DUF5615 family PIN-like protein -
KBZ93_RS18255 (KBZ93_18260) 9205..9621 - 417 WP_011153783.1 hypothetical protein -
KBZ93_RS18260 (KBZ93_18265) 9713..9940 + 228 WP_011153784.1 DUF2281 domain-containing protein Antitoxin
KBZ93_RS18265 (KBZ93_18270) 9948..10373 + 426 WP_011153785.1 PIN domain-containing protein Toxin
KBZ93_RS18270 (KBZ93_18275) 10395..10994 + 600 WP_011153786.1 ParA family protein -
KBZ93_RS18275 (KBZ93_18280) 10998..11867 + 870 WP_011153787.1 ParB/RepB/Spo0J family partition protein -
KBZ93_RS18280 (KBZ93_18285) 12618..13181 - 564 WP_199303651.1 hypothetical protein -
KBZ93_RS18285 (KBZ93_18290) 13695..15104 - 1410 WP_223211249.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
inside Non-Mobilizable plasmid - - 1..44343 44343


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-116)

Antitoxin

Domain of unknown function DUF2281

(6-66)


Sequences

Toxin        


Download         Length: 142 a.a.        Molecular weight: 15962.62 Da        Isoelectric Point: 4.3429

>T199528 WP_011153785.1 NZ_CP073021:9948-10373 [Synechocystis sp. PCC 6803]
VKVLLDTNIVLDLLLEREPFIEETIAIFEEIEQGNIEAYIAATTVTNIFYIIRKNKSREVALIAVKRLLIGLQLCPVNLQ
VIEVALDINLRDFEDSVQLACATVNQLTAIITRDTKDFVESPLPIYSPAECLYRVKTNKLD

Download         Length: 426 bp

>T199528 NZ_CP097372:33597-33845 [Escherichia coli]
ATGAGAAAAAATAAAGGCGATGTGACTTATTTTCTTGAAAAAGAAGGTGACAATTACAGGCTTACAAAAAGGATAAAAGC
CAGAACAAATGTTAAAATCGGGAACAAAACTACGAAAATTACATTGTATGATGCCGTACTGAATGAGAATGAATTACAAC
ATATTGATTTTACGTGTGCCGGATTAAGGGAAGACGATGAGACGCCAGTTAAAAATTTAATTAAGGAGTTTATGTTAAAT
GAAACCTGA

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8420.71 Da        Isoelectric Point: 6.2748

>AT199528 WP_011153784.1 NZ_CP073021:9713-9940 [Synechocystis sp. PCC 6803]
MTAQEKLYQLIQTLPEKEVSEILNFAESLWPKVSSPKIPAGTLTGLRGIAKPTGPVPSDAELQRQYTDYLKEKYL

Download         Length: 228 bp

>AT199528 NZ_CP097372:33835-34062 [Escherichia coli]
ATGAAACCTGATAATACACCTGAAAATGTAAAAAAATTACGTTTAAAAGCAGGATTAACACAAAAGGAATGCAGTCATAT
TTATGGTGTTGGGCTAAGAACCTGGCAGAAAAAAGAGGAAGTTAATACTCAAAACAGTCAAAGTCTGTCACTGGTTGAGT
TTGAGTTTCTTTTGTTACTTGCAGGAGAACATCCTGAATACGTGCTCTGCAAAAGGGAGTCAAAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References