Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/Txe-RelB
Location 13694..14196 Replicon plasmid pF162_2_2
Accession NZ_CP072890
Organism Enterococcus raffinosus strain F162_2

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag J9537_RS20380 Protein ID WP_125395864.1
Coordinates 13694..13960 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag J9537_RS20385 Protein ID WP_125395862.1
Coordinates 13945..14196 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J9537_RS20360 (J9537_20360) 9031..9315 - 285 WP_000922261.1 hypothetical protein -
J9537_RS20365 (J9537_20365) 9508..9729 - 222 Protein_11 hypothetical protein -
J9537_RS20370 (J9537_20370) 10303..11955 - 1653 WP_125395868.1 ATP-binding protein -
J9537_RS20375 (J9537_20375) 11942..13315 - 1374 WP_125395866.1 SIR2 family protein -
J9537_RS20380 (J9537_20380) 13694..13960 - 267 WP_125395864.1 Txe/YoeB family addiction module toxin Toxin
J9537_RS20385 (J9537_20385) 13945..14196 - 252 WP_125395862.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
J9537_RS20390 (J9537_20390) 14359..14730 - 372 WP_125395860.1 hypothetical protein -
J9537_RS20395 (J9537_20395) 14732..15643 - 912 WP_002333825.1 AAA family ATPase -
J9537_RS20400 (J9537_20400) 16196..17695 + 1500 WP_193809672.1 primase C-terminal domain-containing protein -
J9537_RS20405 (J9537_20405) 17832..18119 + 288 WP_010782322.1 hypothetical protein -
J9537_RS20410 (J9537_20410) 18285..18622 - 338 Protein_20 transposase -
J9537_RS20415 (J9537_20415) 18570..18779 + 210 WP_218257691.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Mobilizable plasmid dfrG / ant(6)-Ia / lsa(E) / lnu(B) / aph(3')-III / erm(B) - 1..37686 37686


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-57)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10350.10 Da        Isoelectric Point: 10.3480

>T199082 WP_125395864.1 NZ_CP072890:c13960-13694 [Enterococcus raffinosus]
MGYNVKIKKNARKDLPKLKSVNLASKFDELIKVIKENPFQTPPPYEKLTGLPYYSRRLNIKHRLVYSVEEESKTITILSV
WSHYERGL

Download         Length: 267 bp

>T199082 NZ_CP097172:48044-48196 [Escherichia coli]
ATGCCACAGCGAACGTTTTTAATGATGTTAATCGTCATCTGTGTGACGATTCTGTGTTTTGTCTGGATGGTGAGGGATTC
GCTTTGCGGACTCCGGCTCCAGCAGGGAAACACAGTGCTTGTGGCAACGTTAGCCTACGAAGTTAAACGTTAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9496.57 Da        Isoelectric Point: 4.0940

>AT199082 WP_125395862.1 NZ_CP072890:c14196-13945 [Enterococcus raffinosus]
MEVITPTNARKNLYGIIKHVVSDSQPVEIASTKEEESVIMISKSDWNSLQETIYLQNAGVLDRIKHFDNEESEDLGEIDW
DTM

Download         Length: 252 bp

>AT199082 NZ_CP097172:c47994-47932 [Escherichia coli]
TCGAAGCATTACAGTAGAGCCCTTGGTTGATTGATAAAAAAATCTCCAGGGGCTTTCTGCTGT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References