Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
| Location | 4361175..4361746 | Replicon | chromosome |
| Accession | NZ_CP072455 | ||
| Organism | Xenorhabdus budapestensis strain C-7-2 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | - |
| Locus tag | HGO23_RS19880 | Protein ID | WP_280529549.1 |
| Coordinates | 4361175..4361333 (+) | Length | 53 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | HGO23_RS19455 | Protein ID | WP_244967851.1 |
| Coordinates | 4361417..4361746 (+) | Length | 110 a.a. |
Genomic Context
Location: 4357200..4360151 (2952 bp)
Type: Others
Protein ID: WP_209027545.1
Type: Others
Protein ID: WP_209027545.1
Location: 4360160..4360975 (816 bp)
Type: Others
Protein ID: WP_209027546.1
Type: Others
Protein ID: WP_209027546.1
Location: 4361175..4361333 (159 bp)
Type: Toxin
Protein ID: WP_280529549.1
Type: Toxin
Protein ID: WP_280529549.1
Location: 4361417..4361746 (330 bp)
Type: Antitoxin
Protein ID: WP_244967851.1
Type: Antitoxin
Protein ID: WP_244967851.1
Location: 4361893..4363257 (1365 bp)
Type: Others
Protein ID: WP_209027547.1
Type: Others
Protein ID: WP_209027547.1
Location: 4363350..4364981 (1632 bp)
Type: Others
Protein ID: WP_209027548.1
Type: Others
Protein ID: WP_209027548.1
Location: 4364984..4365244 (261 bp)
Type: Others
Protein ID: WP_099136768.1
Type: Others
Protein ID: WP_099136768.1
Location: 4365208..4365567 (360 bp)
Type: Others
Protein ID: WP_099136767.1
Type: Others
Protein ID: WP_099136767.1
Location: 4365585..4365725 (141 bp)
Type: Others
Protein ID: WP_038267117.1
Type: Others
Protein ID: WP_038267117.1
Loading, please wait
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HGO23_RS19440 (HGO23_19440) | 4357200..4360151 | + | 2952 | WP_209027545.1 | TonB-dependent receptor | - |
| HGO23_RS19445 (HGO23_19445) | 4360160..4360975 | + | 816 | WP_209027546.1 | energy transducer TonB | - |
| HGO23_RS19880 (HGO23_19450) | 4361175..4361333 | + | 159 | WP_280529549.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| HGO23_RS19455 (HGO23_19455) | 4361417..4361746 | + | 330 | WP_244967851.1 | HigA family addiction module antitoxin | Antitoxin |
| HGO23_RS19460 (HGO23_19460) | 4361893..4363257 | - | 1365 | WP_209027547.1 | tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE | - |
| HGO23_RS19465 (HGO23_19465) | 4363350..4364981 | - | 1632 | WP_209027548.1 | membrane protein insertase YidC | - |
| HGO23_RS19470 (HGO23_19470) | 4364984..4365244 | - | 261 | WP_099136768.1 | membrane protein insertion efficiency factor YidD | - |
| HGO23_RS19475 (HGO23_19475) | 4365208..4365567 | - | 360 | WP_099136767.1 | ribonuclease P protein component | - |
| HGO23_RS19480 (HGO23_19480) | 4365585..4365725 | - | 141 | WP_038267117.1 | 50S ribosomal protein L34 | - |
Associated MGEs
Loading, please wait
MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 53 a.a. Molecular weight: 5910.75 Da Isoelectric Point: 8.0214
>T197788 WP_280529549.1 NZ_CP072455:4361175-4361333 [Xenorhabdus budapestensis]
IPSTIEGVLFRKLQILDAATQESDLRIPPGNRFEHLQGNLSGWCSIRVNKQY
IPSTIEGVLFRKLQILDAATQESDLRIPPGNRFEHLQGNLSGWCSIRVNKQY
Download Length: 159 bp
>T197788 NZ_CP096715:3226-3582 [Acinetobacter baumannii]
ATGTGGACAGTCATTACAACGGATCTGTTTAATGAATGGCTTGAACAGCAAGATGAAGCAACACAAGAGAAAGTCTTAGC
TGCATTGGTTGTTCTACAACAGCAAGGGCCTAGTTTAGGTCGTCCTTTAGTAGATACCGTCTACGATTCTAAATTTACCA
ATATGAAGGAACTACGTGTTCAGCATCGTGGTAAACCGTTAAGGGCATTTTTTGCATTCGATCCCCTAAGACAAGCGATT
GTGCTGTGTATTGGTGATAAGAGTAATAAAAAGCGTTTTTATACAGAGATGCTAGCAATTGCAGATGAGCAATACGCACT
TCATCTCTCAACTTTAGGAGATCAATCTAATGGCTAA
ATGTGGACAGTCATTACAACGGATCTGTTTAATGAATGGCTTGAACAGCAAGATGAAGCAACACAAGAGAAAGTCTTAGC
TGCATTGGTTGTTCTACAACAGCAAGGGCCTAGTTTAGGTCGTCCTTTAGTAGATACCGTCTACGATTCTAAATTTACCA
ATATGAAGGAACTACGTGTTCAGCATCGTGGTAAACCGTTAAGGGCATTTTTTGCATTCGATCCCCTAAGACAAGCGATT
GTGCTGTGTATTGGTGATAAGAGTAATAAAAAGCGTTTTTATACAGAGATGCTAGCAATTGCAGATGAGCAATACGCACT
TCATCTCTCAACTTTAGGAGATCAATCTAATGGCTAA
Antitoxin
Download Length: 110 a.a. Molecular weight: 12524.45 Da Isoelectric Point: 8.7254
>AT197788 WP_244967851.1 NZ_CP072455:4361417-4361746 [Xenorhabdus budapestensis]
MRNTKRRPVTVGQMLVTEFLEPMNIEISELAEAMGVHRNTLSRIVHDKGNLTASMAIKLAVALGNTPEFWLNIQHAVELW
DVRHKAYEQEAKNVKQVRPHLEHSEVAFR
MRNTKRRPVTVGQMLVTEFLEPMNIEISELAEAMGVHRNTLSRIVHDKGNLTASMAIKLAVALGNTPEFWLNIQHAVELW
DVRHKAYEQEAKNVKQVRPHLEHSEVAFR
Download Length: 330 bp
>AT197788 NZ_CP096715:3575-3877 [Acinetobacter baumannii]
ATGGCTAAGAGCTTACAAGAATTATTGGCTAGTCGCTCTCCAGAGAGTCAAGCTCGTATTCAAAAAATGGCTGATGAATT
ACTTTTAGAAAGTCAGCTTCACCTTATCCGAGAAGAGTTAGAAATTTCCCAGAAAGAACTAGCTGCAACCCTTGGAATTA
AACAGCCGTCATTATCAGCAATCGAAAATCGTGGTCATGATCTTAAAATTTCAACGATGAAAAAGTATGTTGAAGCAATG
GGTGGAAAACTTCGTATTGATGTAGAGCTTCCAACAGGAAAACACATAGGGTTCAATGTCTAA
ATGGCTAAGAGCTTACAAGAATTATTGGCTAGTCGCTCTCCAGAGAGTCAAGCTCGTATTCAAAAAATGGCTGATGAATT
ACTTTTAGAAAGTCAGCTTCACCTTATCCGAGAAGAGTTAGAAATTTCCCAGAAAGAACTAGCTGCAACCCTTGGAATTA
AACAGCCGTCATTATCAGCAATCGAAAATCGTGGTCATGATCTTAAAATTTCAACGATGAAAAAGTATGTTGAAGCAATG
GGTGGAAAACTTCGTATTGATGTAGAGCTTCCAACAGGAAAACACATAGGGTTCAATGTCTAA