Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 1411281..1411783 Replicon chromosome
Accession NZ_CP072455
Organism Xenorhabdus budapestensis strain C-7-2

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag HGO23_RS06815 Protein ID WP_209028381.1
Coordinates 1411529..1411783 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag HGO23_RS06810 Protein ID WP_209028380.1
Coordinates 1411281..1411526 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
HGO23_RS06795 (HGO23_06795) 1406543..1407445 + 903 WP_099137250.1 DNA-3-methyladenine glycosylase 2 -
HGO23_RS06800 (HGO23_06800) 1408500..1409627 + 1128 Protein_1348 ISAs1 family transposase -
HGO23_RS06810 (HGO23_06810) 1411281..1411526 + 246 WP_209028380.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
HGO23_RS06815 (HGO23_06815) 1411529..1411783 + 255 WP_209028381.1 Txe/YoeB family addiction module toxin Toxin
HGO23_RS06820 (HGO23_06820) 1411893..1412915 + 1023 WP_209027922.1 IS110 family transposase -
HGO23_RS06825 (HGO23_06825) 1413143..1414027 - 885 Protein_1353 IS982 family transposase -
HGO23_RS06830 (HGO23_06830) 1414471..1414797 - 327 Protein_1354 ISAs1 family transposase -
HGO23_RS06835 (HGO23_06835) 1414821..1415531 - 711 Protein_1355 IS110 family transposase -
HGO23_RS06840 (HGO23_06840) 1415777..1416736 + 960 WP_209028382.1 IS110 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1357211..1423741 66530
- inside IScluster/Tn - - 1408500..1415414 6914


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10257.91 Da        Isoelectric Point: 9.4092

>T197785 WP_209028381.1 NZ_CP072455:1411529-1411783 [Xenorhabdus budapestensis]
MNLIFTDESWSDYLYWQQIDKKIIKRINELIKDIKRTPFIGIGKPEPLKHNLTGFWSRRISDEHRLIYRVTEMGLEIVSC
RYHY

Download         Length: 255 bp

>T197785 NZ_CP096713:c21108-20821 [Acinetobacter baumannii]
ATGGAACAGTATTTTGAATGGGATGAGGCTAAGAATCGAAAGAATCAGAAAAAGCATGATATCTCTTTCGAAACTGCAAG
CCTTGTTTTTGAAGATCCATTACGGATCTCAATCCAAGACAGATATACTAATGGTGAAGAACGTTGGCAAACCATTGGAC
GAGTTAAAGGCGTACTAATGTTATTGGTGGCTCACACCATTTTTGATGAAGATGACTGTGAAATCATCCGAATCATTAGT
GCAAGGCAAGTCACTAAAGCGGAGCGAAACAAATATGAGCATGGTTAG

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9275.66 Da        Isoelectric Point: 6.9753

>AT197785 WP_209028380.1 NZ_CP072455:1411281-1411526 [Xenorhabdus budapestensis]
MKTVNYTDARQNLTSIMNETIDDRVPILITRQKGVPCVLLSYDEYRSLEETSYLLRSPANARHLMDSIDSLNKGKGMIKE
I

Download         Length: 246 bp

>AT197785 NZ_CP096713:c20834-20520 [Acinetobacter baumannii]
ATGAGCATGGTTAGATACTCACACAAAGAGCTGAATGAGAAATTTGGTGAGAAGCAAGATGCTGAAATTCAACGCTTGCT
TGCTAAAGGCACGGTTCCTGATGATCAGCTAGATCTATCAGATATTCCTGAAATTACAGACTGGAGCAATGCTGTACGCC
AAAATCAATTTTACCGCCCAGTAAAGCAACAAACTTCAATTCGGTTAGATGCTGATGTACTTGCTTGGTTCAAAGCACAA
GGCAAAGGTTATCAAACACGTATGAATGAAATTTTACGAGATGCTATGCTAAAAGAATTAAAAAATCATCAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References