Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | higBA (relBE)/Tad-HTH_37 |
Location | 960165..960763 | Replicon | chromosome |
Accession | NZ_CP072455 | ||
Organism | Xenorhabdus budapestensis strain C-7-2 |
Toxin (Protein)
Gene name | higB | Uniprot ID | - |
Locus tag | HGO23_RS04310 | Protein ID | WP_187650600.1 |
Coordinates | 960443..960763 (-) | Length | 107 a.a. |
Antitoxin (Protein)
Gene name | higA | Uniprot ID | - |
Locus tag | HGO23_RS04305 | Protein ID | WP_209028081.1 |
Coordinates | 960165..960446 (-) | Length | 94 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
HGO23_RS04280 (HGO23_04280) | 956360..956674 | + | 315 | WP_209028077.1 | hypothetical protein | - |
HGO23_RS04285 (HGO23_04285) | 956676..957356 | + | 681 | WP_209028078.1 | hypothetical protein | - |
HGO23_RS04290 (HGO23_04290) | 957511..958629 | + | 1119 | WP_244967946.1 | phage tail protein | - |
HGO23_RS04295 (HGO23_04295) | 958678..959544 | - | 867 | WP_209028080.1 | phage tail protein | - |
HGO23_RS04300 (HGO23_04300) | 959842..960125 | + | 284 | Protein_848 | helix-turn-helix transcriptional regulator | - |
HGO23_RS04305 (HGO23_04305) | 960165..960446 | - | 282 | WP_209028081.1 | helix-turn-helix transcriptional regulator | Antitoxin |
HGO23_RS04310 (HGO23_04310) | 960443..960763 | - | 321 | WP_187650600.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
HGO23_RS04315 (HGO23_04315) | 961145..962302 | - | 1158 | WP_209028082.1 | site-specific integrase | - |
HGO23_RS04320 (HGO23_04320) | 962697..963092 | - | 396 | WP_209028083.1 | hypothetical protein | - |
HGO23_RS04325 (HGO23_04325) | 963369..963980 | - | 612 | WP_209028084.1 | XRE family transcriptional regulator | - |
HGO23_RS04330 (HGO23_04330) | 964163..964399 | + | 237 | WP_209028087.1 | YdaS family helix-turn-helix protein | - |
HGO23_RS04335 (HGO23_04335) | 964467..965249 | + | 783 | WP_209028089.1 | helix-turn-helix domain-containing protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Integrative and Conjugative Element | - | - | 910691..1142970 | 232279 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 107 a.a. Molecular weight: 12056.16 Da Isoelectric Point: 9.7884
>T197781 WP_187650600.1 NZ_CP072455:c960763-960443 [Xenorhabdus budapestensis]
MSWNIDFYHGVMDSILDMPPKIQARMLKLLELMEQHGANLGSPHTEPMGNGLFEVRAKAQEGIGRGLFCYLDGSHIYILH
AFVKKSQKTPKKDLDLAKSRMKEVKK
MSWNIDFYHGVMDSILDMPPKIQARMLKLLELMEQHGANLGSPHTEPMGNGLFEVRAKAQEGIGRGLFCYLDGSHIYILH
AFVKKSQKTPKKDLDLAKSRMKEVKK
Download Length: 321 bp
>T197781 NZ_CP096707:1613821-1614003 [Acinetobacter baumannii]
GTGAAAAGTCTGGATTTAATCAAAATGATTGAAGCAGATGGTTGGTATGAGGTTAGGGTTTCAGGAAGTCATCATCACTT
TAAACACCCAACCAAAAAGGGGTTAGTTACAATCCCACATCCTAAAAAGGATTTACCAAACGGAACTGTTAAAAGCATTT
TGAAACAAGCGGGTCTAAATTGA
GTGAAAAGTCTGGATTTAATCAAAATGATTGAAGCAGATGGTTGGTATGAGGTTAGGGTTTCAGGAAGTCATCATCACTT
TAAACACCCAACCAAAAAGGGGTTAGTTACAATCCCACATCCTAAAAAGGATTTACCAAACGGAACTGTTAAAAGCATTT
TGAAACAAGCGGGTCTAAATTGA
Antitoxin
Download Length: 94 a.a. Molecular weight: 10592.98 Da Isoelectric Point: 8.9375
>AT197781 WP_209028081.1 NZ_CP072455:c960446-960165 [Xenorhabdus budapestensis]
MSQLQALKAKALQNPEVKQAYDELNDEFEFINTLLSMRTEAKLTQQQVADRMGTKESNISRLEKGKSNPTLSTLVNYAKA
CGFQLDFSYRRNS
MSQLQALKAKALQNPEVKQAYDELNDEFEFINTLLSMRTEAKLTQQQVADRMGTKESNISRLEKGKSNPTLSTLVNYAKA
CGFQLDFSYRRNS
Download Length: 282 bp
>AT197781 NZ_CP096707:1614096-1614500 [Acinetobacter baumannii]
ATGTTATATCCAATTGCAATTGAACGAGGATCAGATACTGAGGCATTTGGTGTCACTGTTCCTGATATTCCAGGTTGTTT
TAGTGCTGGTGACACACTTGAAGAAGCTATTGAGAATGTTAAAGAAGCTATTTCAGGCCATTTAGAAATATTGGCTGAAG
ATGGTGAGGAAATCCCATTAGCTTCCGAACTAGTTAAATTTGTCGATGATCCTGAATATAAAGGAATGATCTGGGCGGTT
ACCGAAGTTGATGTTAGTCGTTATCTGGGTAAACCAGAAAAAATCAATGTTACTTTACCAAGCCGTTTGATTCGTAAAAT
TGATGAGAATGTAGGTAAAGGTAAGAGATATACTACTCGATCGGCTTTCTTGGCTGCTGGTGCTGAAAAACTTTTACATG
CATAG
ATGTTATATCCAATTGCAATTGAACGAGGATCAGATACTGAGGCATTTGGTGTCACTGTTCCTGATATTCCAGGTTGTTT
TAGTGCTGGTGACACACTTGAAGAAGCTATTGAGAATGTTAAAGAAGCTATTTCAGGCCATTTAGAAATATTGGCTGAAG
ATGGTGAGGAAATCCCATTAGCTTCCGAACTAGTTAAATTTGTCGATGATCCTGAATATAAAGGAATGATCTGGGCGGTT
ACCGAAGTTGATGTTAGTCGTTATCTGGGTAAACCAGAAAAAATCAATGTTACTTTACCAAGCCGTTTGATTCGTAAAAT
TGATGAGAATGTAGGTAAAGGTAAGAGATATACTACTCGATCGGCTTTCTTGGCTGCTGGTGCTGAAAAACTTTTACATG
CATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Structures
Toxin
Source | ID | Structure |
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Antitoxin
Source | ID | Structure |
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