197674

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 618008..618515 Replicon chromosome
Accession NZ_CP072385
Organism Arachnia propionica strain F0714

Toxin (Protein)


Gene name yoeB Uniprot ID A0A4V1GCM1
Locus tag J5A53_RS02705 Protein ID WP_014847590.1
Coordinates 618261..618515 (+) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A3N4D924
Locus tag J5A53_RS02700 Protein ID WP_014847591.1
Coordinates 618008..618259 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5A53_RS02675 (J5A53_02675) 613388..614425 - 1038 WP_051015057.1 DUF2330 domain-containing protein -
J5A53_RS02680 (J5A53_02680) 614501..614884 - 384 WP_014847595.1 helix-turn-helix domain-containing protein -
J5A53_RS02685 (J5A53_02685) 615006..615959 + 954 WP_014847594.1 NmrA/HSCARG family protein -
J5A53_RS02690 (J5A53_02690) 615946..617175 - 1230 WP_014847593.1 MFS transporter -
J5A53_RS02695 (J5A53_02695) 617246..617830 + 585 WP_014847592.1 TetR/AcrR family transcriptional regulator -
J5A53_RS02700 (J5A53_02700) 618008..618259 + 252 WP_014847591.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
J5A53_RS02705 (J5A53_02705) 618261..618515 + 255 WP_014847590.1 Txe/YoeB family addiction module toxin Toxin
J5A53_RS02710 (J5A53_02710) 618574..618855 - 282 WP_123824087.1 hypothetical protein -
J5A53_RS02715 (J5A53_02715) 619174..619410 + 237 WP_014847589.1 antitoxin -
J5A53_RS02720 (J5A53_02720) 619418..620242 - 825 WP_014847588.1 class I SAM-dependent methyltransferase -
J5A53_RS15795 620314..620913 - 600 WP_245528507.1 hypothetical protein -
J5A53_RS15800 620912..621697 + 786 WP_051015054.1 MFS transporter -
J5A53_RS02730 (J5A53_02730) 621802..622275 + 474 WP_014847587.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(2-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-69)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9826.09 Da        Isoelectric Point: 6.4548

>T197674 WP_014847590.1 NZ_CP072385:618261-618515 [Arachnia propionica]
VRLAWDPSAWEDYTYWQAADSRILKRINALIDTCLRDPFGGIGKPEQLRYGATGAWSRRITEEHRLVYLVDGDDLVILQA
RYHY

Download         Length: 255 bp

>T197674 NZ_CP096570:c917497-917363 [Xanthomonas translucens pv. undulosa]
ATGAAGCGTACTTTCGCGTGGATGCTGCTGGCGATGTTCTCGGTGGGCCTGCTGTCGGGCTGCAACACGGTTGCCGGTGC
CGGCAAGGACGTGAAGAGCGCCGGCGAGAAGGTCGAAGACGCCGCCAAGAACTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9497.50 Da        Isoelectric Point: 4.6794

>AT197674 WP_014847591.1 NZ_CP072385:618008-618259 [Arachnia propionica]
VSISASEARRTLFPLIEQVNDDRTAVEIVSRKGNAVLMSADEYAAWQETAYLFRSPANARRLLDAYERAREGRSEEHDLI
RED

Download         Length: 252 bp

>AT197674 NZ_CP096570:c917748-917596 [Xanthomonas translucens pv. undulosa]
ATGAAGCGACTGTTCACCTTGACGATGCTGACCCTGTTTTGTGCAGGCATGCTGACCGGCTGCAACACCATGGCCGGCGC
CGGTAAGGACATGCAGAAGGCCGGCGATAAGGTGGAAACCAAGGCCGACGACTGTAAAGACGGCAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A4V1GCM1

Antitoxin

Source ID Structure
AlphaFold DB A0A3N4D924

References