Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
| Location | 1949959..1950658 | Replicon | chromosome |
| Accession | NZ_CP072167 | ||
| Organism | Agrobacterium larrymoorei strain AF3.44 | ||
Toxin (Protein)
| Gene name | mqsR | Uniprot ID | A0A4D7DRI6 |
| Locus tag | J5285_RS09230 | Protein ID | WP_027675444.1 |
| Coordinates | 1950362..1950658 (-) | Length | 99 a.a. |
Antitoxin (Protein)
| Gene name | mqsA | Uniprot ID | A0A4D7DPV9 |
| Locus tag | J5285_RS09225 | Protein ID | WP_027675445.1 |
| Coordinates | 1949959..1950360 (-) | Length | 134 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J5285_RS09205 (J5285_09210) | 1945055..1946449 | - | 1395 | WP_027675449.1 | FAD-binding oxidoreductase | - |
| J5285_RS09210 (J5285_09215) | 1946760..1948424 | + | 1665 | WP_027675448.1 | electron transfer flavoprotein-ubiquinone oxidoreductase | - |
| J5285_RS09215 (J5285_09220) | 1948456..1948959 | + | 504 | WP_051441274.1 | GNAT family N-acetyltransferase | - |
| J5285_RS09220 (J5285_09225) | 1949115..1949861 | + | 747 | WP_027675446.1 | pentapeptide repeat-containing protein | - |
| J5285_RS09225 (J5285_09230) | 1949959..1950360 | - | 402 | WP_027675445.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
| J5285_RS09230 (J5285_09235) | 1950362..1950658 | - | 297 | WP_027675444.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
| J5285_RS09235 (J5285_09240) | 1950764..1951780 | - | 1017 | WP_027675443.1 | zinc-binding alcohol dehydrogenase family protein | - |
| J5285_RS09240 (J5285_09245) | 1951918..1952316 | + | 399 | WP_027675442.1 | helix-turn-helix domain-containing protein | - |
| J5285_RS09245 (J5285_09250) | 1952313..1953710 | + | 1398 | WP_027675441.1 | coniferyl aldehyde dehydrogenase | - |
| J5285_RS09250 (J5285_09255) | 1953839..1954675 | + | 837 | WP_027675440.1 | undecaprenyl-diphosphate phosphatase | - |
| J5285_RS09255 (J5285_09260) | 1954775..1955056 | - | 282 | WP_027675439.1 | XRE family transcriptional regulator | - |
| J5285_RS09260 (J5285_09265) | 1955053..1955382 | - | 330 | WP_037170972.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11165.86 Da Isoelectric Point: 6.9886
>T197452 WP_027675444.1 NZ_CP072167:c1950658-1950362 [Agrobacterium larrymoorei]
MEKTAPHTVLEDVWRLLDEGKVRETFSALSGAAALGMSRSDMHDVVRALSLKDFFKSMTAYHDENVWHDVYKPVTPFGHL
YVKLIVSNNVLIVSFKEK
MEKTAPHTVLEDVWRLLDEGKVRETFSALSGAAALGMSRSDMHDVVRALSLKDFFKSMTAYHDENVWHDVYKPVTPFGHL
YVKLIVSNNVLIVSFKEK
Download Length: 297 bp
>T197452 NZ_CP096187:1711695-1712216 [Enterobacter roggenkampii]
GTGGACAATCTCACGATCGAAATGTTTTCAGAGGGAAAAGACTATGATTTCAGGGACTTCGATTGTGGTGAACCCTCGCT
AAATGTCTTCCTCACAGAACATCTGGTGCGTCAGCACAATGGGCGTATTTTACGAGGCTATTTGCTTAAAGATCGCGATG
GTCCGCGAGTCCTGGGCTATTACACGTTGTCTGGTAGTTGCTTTGAAAAAGCGATGCTGCCTTCTAAGACTCAGCAGCGT
CGGATCCCTTATAGCAACGTACCGAGCGTAACGCTGGGACGTCTGGCGATACATAAAGACTTACAGGGGCTGGAGTGGGG
AACGACGCTCGTCACGCATGCCATGCGGGTTGTCTATCTGGCATCGCAGGCGGTGGGCGTACACGGAATATTTGTTGATG
CACTCAACGACCAGGCAAAACAATTTTATCTGAAGCAGGGCTTTATTCCGCTGACGGATGAAAACAGCCATTCTCTTTTC
TTTCCTACAAAATCTATCGAACGACTGTTTGAGCAGGCGTGA
GTGGACAATCTCACGATCGAAATGTTTTCAGAGGGAAAAGACTATGATTTCAGGGACTTCGATTGTGGTGAACCCTCGCT
AAATGTCTTCCTCACAGAACATCTGGTGCGTCAGCACAATGGGCGTATTTTACGAGGCTATTTGCTTAAAGATCGCGATG
GTCCGCGAGTCCTGGGCTATTACACGTTGTCTGGTAGTTGCTTTGAAAAAGCGATGCTGCCTTCTAAGACTCAGCAGCGT
CGGATCCCTTATAGCAACGTACCGAGCGTAACGCTGGGACGTCTGGCGATACATAAAGACTTACAGGGGCTGGAGTGGGG
AACGACGCTCGTCACGCATGCCATGCGGGTTGTCTATCTGGCATCGCAGGCGGTGGGCGTACACGGAATATTTGTTGATG
CACTCAACGACCAGGCAAAACAATTTTATCTGAAGCAGGGCTTTATTCCGCTGACGGATGAAAACAGCCATTCTCTTTTC
TTTCCTACAAAATCTATCGAACGACTGTTTGAGCAGGCGTGA
Antitoxin
Download Length: 134 a.a. Molecular weight: 14521.51 Da Isoelectric Point: 5.2501
>AT197452 WP_027675445.1 NZ_CP072167:c1950360-1949959 [Agrobacterium larrymoorei]
MACPICGADAVTKETRDLEYSYKGQVTTIPHVTGTFCSACGEAILEGEESERVSAAMLAFNRQVNASFVDPEFIATVRKK
LSLDQREAGDLFGGGVNAFSRYENGKSRPPRSLIQLLKILEKHPDLLDEIKAA
MACPICGADAVTKETRDLEYSYKGQVTTIPHVTGTFCSACGEAILEGEESERVSAAMLAFNRQVNASFVDPEFIATVRKK
LSLDQREAGDLFGGGVNAFSRYENGKSRPPRSLIQLLKILEKHPDLLDEIKAA
Download Length: 402 bp
>AT197452 NZ_CP096187:1711419-1711688 [Enterobacter roggenkampii]
ATGCCAGCACTGAAAAAACAGCGTATCGATCTTCGCTTAACGGACGAAGACAAAACAATGATTGAAGAAGCGGCAGCGAT
GACGAACCAAACGATCACCCAGTTTATGGTGAACAGTGCGTCAGAGCGGGCAGCGGAAGTTATCGAGCAGCACCGCCGTC
TCGTATTAAACGAAGCATCATGGAATGCCGTGATGGATGCCATCGAGAATCCGCCAGAGCCAAATGAACGCCTGAAGCGA
GCGGCGAAACGTCTTCGAAACATGGAGTGA
ATGCCAGCACTGAAAAAACAGCGTATCGATCTTCGCTTAACGGACGAAGACAAAACAATGATTGAAGAAGCGGCAGCGAT
GACGAACCAAACGATCACCCAGTTTATGGTGAACAGTGCGTCAGAGCGGGCAGCGGAAGTTATCGAGCAGCACCGCCGTC
TCGTATTAAACGAAGCATCATGGAATGCCGTGATGGATGCCATCGAGAATCCGCCAGAGCCAAATGAACGCCTGAAGCGA
GCGGCGAAACGTCTTCGAAACATGGAGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A4D7DRI6 |
Antitoxin
| Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A4D7DPV9 |