197423

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 1294244..1294835 Replicon chromosome
Accession NZ_CP072156
Organism Rhizobium sp. B230/85

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag J5289_RS06155 Protein ID WP_209182967.1
Coordinates 1294244..1294528 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag J5289_RS06160 Protein ID WP_209182968.1
Coordinates 1294539..1294835 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5289_RS06140 (J5289_06140) 1290252..1290803 + 552 WP_209182965.1 LemA family protein -
J5289_RS06145 (J5289_06145) 1290899..1292173 + 1275 WP_209182966.1 3-phosphoshikimate 1-carboxyvinyltransferase -
J5289_RS06150 (J5289_06150) 1292219..1294162 + 1944 WP_209183018.1 DUF2207 domain-containing protein -
J5289_RS06155 (J5289_06155) 1294244..1294528 + 285 WP_209182967.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J5289_RS06160 (J5289_06160) 1294539..1294835 + 297 WP_209182968.1 HigA family addiction module antitoxin Antitoxin
J5289_RS06165 (J5289_06165) 1294941..1297175 + 2235 WP_209206715.1 glycine--tRNA ligase subunit beta -
J5289_RS06170 (J5289_06170) 1297208..1297804 - 597 WP_142824153.1 histidine phosphatase family protein -
J5289_RS06175 (J5289_06175) 1297974..1299791 - 1818 WP_209182970.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(15-94)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-92)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10505.98 Da        Isoelectric Point: 7.2774

>T197423 WP_209182967.1 NZ_CP072156:1294244-1294528 [Rhizobium sp. B230/85]
MVILSFKDGSTRAVASGVVPKGFPADLARRAIRKLTMIEYANQLSDLRSPPANHLEALKGDRAGQHSIRINDQWRICFVW
TDAGVEDVEIVDYH

Download         Length: 285 bp

>T197423 NZ_CP096166:c299244-298945 [Shewanella sp. JNE7]
ATGAAAAATAAACGCTATAAACTGAGTAAGTTAGCTCAAACTCACTTACTAAAGATTAAAGACTACACCATTCAACACTT
TTCTGAGTCGCAGTGGCACAAATACAAAGAAAGCCTAATATCCGGCTTGCAAATGTTAGCCGATAACCCCGGATTAGGCA
GAAGCTGCGAAGATATTTACCCCAACGGATTCTACTTTCCGATTGCTAAACACACCGCCTACTTCACAAAAGAAGACGAC
TTCATCCTCATCGTTGCCCTGTTAGGCCAGCCACAACTACCACAAAATCATCTGAAATAG

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11204.13 Da        Isoelectric Point: 8.6091

>AT197423 WP_209182968.1 NZ_CP072156:1294539-1294835 [Rhizobium sp. B230/85]
MKHILPPVHPGEILREEYLAPLKMSAGALARKLNVPRTRIERLVAEETPVTIDTALRLARFFDTTPEFWMNMQTGYELKR
QAEEKRAEIAAIPVLHVA

Download         Length: 297 bp

>AT197423 NZ_CP096166:c299495-299253 [Shewanella sp. JNE7]
GTGCAAACATTAACAGCCAATGACGCCAAACGAAATTTCGGTGAGTTACTGCTAAACGCTCAACGTGAACCCATCAAGAT
CAGCAAAAACAGTAAAGATGCGGTTGTTGTGATGTCTATTCACGACTTCGAACAACTTGAGGCGATGAAAGCGGATTACC
TTAAACACTGCTTCAACGCTGCTAAAGAAGACTTAGCGAAAGGTAATATTGTTGATGGTGAAGATTTTCTTAACGCCCTG
TAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References