Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 3783085..3783676 Replicon chromosome
Accession NZ_CP072146
Organism Rhizobium sp. K1/93

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag J5287_RS18445 Protein ID WP_209182967.1
Coordinates 3783085..3783369 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag J5287_RS18450 Protein ID WP_209182968.1
Coordinates 3783380..3783676 (+) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J5287_RS18430 (J5287_18415) 3779093..3779644 + 552 WP_209182965.1 LemA family protein -
J5287_RS18435 (J5287_18420) 3779740..3781014 + 1275 WP_209182966.1 3-phosphoshikimate 1-carboxyvinyltransferase -
J5287_RS18440 (J5287_18425) 3781060..3783003 + 1944 WP_209183018.1 DUF2207 domain-containing protein -
J5287_RS18445 (J5287_18430) 3783085..3783369 + 285 WP_209182967.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J5287_RS18450 (J5287_18435) 3783380..3783676 + 297 WP_209182968.1 HigA family addiction module antitoxin Antitoxin
J5287_RS18455 (J5287_18440) 3783782..3786016 + 2235 WP_209182969.1 glycine--tRNA ligase subunit beta -
J5287_RS18460 (J5287_18445) 3786049..3786645 - 597 WP_142824153.1 histidine phosphatase family protein -
J5287_RS18465 (J5287_18450) 3786815..3788632 - 1818 WP_209182970.1 methyl-accepting chemotaxis protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(15-94)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-92)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10505.98 Da        Isoelectric Point: 7.2774

>T197405 WP_209182967.1 NZ_CP072146:3783085-3783369 [Rhizobium sp. K1/93]
MVILSFKDGSTRAVASGVVPKGFPADLARRAIRKLTMIEYANQLSDLRSPPANHLEALKGDRAGQHSIRINDQWRICFVW
TDAGVEDVEIVDYH

Download         Length: 285 bp

>T197405 NZ_CP096141:317018-317152 [Xanthomonas prunicola]
ATGAAGCGTGCAATTGTGCTGCTGGTGCTGTCGATGTTGTCGGTCGGTATGCTGTCGGGCTGCAACACCGTCGCAGGTGC
TGGCAAGGACGTGAAGGGTGCTGGCGAGAAGGTGGAAGACGCAGCGCGTAAGTAA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11204.13 Da        Isoelectric Point: 8.6091

>AT197405 WP_209182968.1 NZ_CP072146:3783380-3783676 [Rhizobium sp. K1/93]
MKHILPPVHPGEILREEYLAPLKMSAGALARKLNVPRTRIERLVAEETPVTIDTALRLARFFDTTPEFWMNMQTGYELKR
QAEEKRAEIAAIPVLHVA

Download         Length: 297 bp

>AT197405 NZ_CP096141:316791-316943 [Xanthomonas prunicola]
ATGAAGCGACTGCTGACACTGATGGTACTGGGCCTGTTTTCGGCCGGCGTGATGACGGGCTGCAACACCGTGGCTGGCGC
TGGCAAGGACATGCAGGGCGCAGGTGGGAAGGTCGAGAAAACCGCCGAAAAATGCAGCGACGGTAAGTGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References