Detailed information of TA system TA197320

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2721209..2721487
• Replicon: chromosome
• Accession: NZ_CP072116
• Organism: Staphylococcus aureus strain TCH32929

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: J6L63_RS13575
• Protein ID: WP_001802298.1
• Coordinates: 2721209..2721313 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2721309..2721487 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J6L63_RS13560	2718006..2718788	+	783	WP_000908182.1	ABC transporter ATP-binding protein	-
J6L63_RS13565	2718856..2719713	+	858	WP_000370923.1	HAD family hydrolase	-
J6L63_RS13570	2720371..2720529	-	159	WP_001792784.1	hypothetical protein	-
J6L63_RS13575	2721209..2721313	+	105	WP_001802298.1	hypothetical protein	Toxin
-	2721309..2721487	-	179	-	-	Antitoxin
J6L63_RS13585	2721746..2722837	-	1092	WP_000495669.1	hypothetical protein	-
J6L63_RS13590	2723103..2724080	-	978	WP_000019734.1	CDF family zinc efflux transporter CzrB	-
J6L63_RS13595	2724082..2724402	-	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
J6L63_RS13600	2724554..2725219	+	666	WP_001024095.1	SDR family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T197320 WP_001802298.1 NZ_CP072116:2721209-2721313 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T197320 NZ_CP096016:3644657-3644947 [Alkalimarinus coralli]
ATGATCATTTCCTTTGGCAATAAAGCGACATCAGACCTGTTTAATGGTGTTTCTAGTCGTTGGGTGCGAAAGCTGCCTAA
TCAGATACATGAGTTGGCCTTGTATAAGCTTGATGTTATCAATGCTGCTCAAAACCTTGATGACCTTAAGTCGCCTCCTG
GAAATAGACTTGAGCTGCTCAAAGGTGACTTAGAAGGTTTCCATAGTATTCGTATTAATTCTCAGTGGCGTATTGTATTT
CGCTGGGATTCTAATGCAGCTCATGATGTTCAAATAGTGGATTACCACTAA

Antitoxin

Nucleotide

• Length: 179 bp

>AT197320 NZ_CP072116:c2721487-2721309 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin