Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 2994054..2994643 Replicon chromosome
Accession NZ_CP071891
Organism Xanthomonas oryzae pv. oryzae strain T7133

Toxin (Protein)


Gene name graT Uniprot ID G7TIR7
Locus tag J4Q40_RS14075 Protein ID WP_012443754.1
Coordinates 2994054..2994335 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag J4Q40_RS14080 Protein ID WP_011260746.1
Coordinates 2994353..2994643 (+) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J4Q40_RS14070 2991707..2993959 + 2253 WP_069960050.1 exodeoxyribonuclease V subunit alpha -
J4Q40_RS14075 2994054..2994335 + 282 WP_012443754.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
J4Q40_RS14080 2994353..2994643 + 291 WP_011260746.1 HigA family addiction module antitoxin Antitoxin
J4Q40_RS14085 2995572..2996966 + 1395 WP_027703652.1 type III secretion system effector XopQ -
J4Q40_RS23765 2997069..2997256 - 188 Protein_2712 hypothetical protein -
J4Q40_RS14090 2997416..2997748 - 333 WP_011260743.1 hypothetical protein -
J4Q40_RS14095 2998003..2998329 + 327 WP_228329596.1 hypothetical protein -
J4Q40_RS14100 2998457..2998879 + 423 WP_042465811.1 PAAR domain-containing protein -
J4Q40_RS14105 2998882..2999490 + 609 WP_011409746.1 DUF4123 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(2-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(14-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11066.83 Da        Isoelectric Point: 10.5318

>T197123 WP_012443754.1 NZ_CP071891:2994054-2994335 [Xanthomonas oryzae pv. oryzae]
VIRSFIDKDAEKIWLGERSRRLPADIQLVARRKLRMLNAAAHLDDLRIPPANRLEALKGQRRGQYSIRINDQWRICFRWM
EGDVVQVEIVDYH

Download         Length: 282 bp

>T197123 NZ_CP095736:1922740-1922916 [Bacillus subtilis]
GTGCTTGAGAAAGTGGGTATCATAGTTGCTTTCCTCATATCTTTAACGGTTCTTACAATCAACAGTCTAACAATAGTTGA
GAAGGTAAGAAACCTAAAGAATGGGACAAGCAAAAAGAAAAAGCGTATACGCAAGCGGCTCCGACCAAAGAGACAACGCC
AACATATACGCCGATGA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10420.07 Da        Isoelectric Point: 7.2040

>AT197123 WP_011260746.1 NZ_CP071891:2994353-2994643 [Xanthomonas oryzae pv. oryzae]
MTVLPNIHPGDILLEEFLEPLGISQNALARATGVPPRRINEIVLGKRGITADTAVRLAAALGTSERFWLGLQADYELEQA
HRALGDLPARIKRLAA

Download         Length: 291 bp

>AT197123 NZ_CP095736:c1922799-1922699 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GFW5

Antitoxin

Source ID Structure

References