Detailed information of TA system TA197084

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-RelB
• Location: 2858878..2859386
• Replicon: chromosome
• Accession: NZ_CP071869
• Organism: Polaribacter cellanae strain SM13

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: J3359_RS12895
• Protein ID: WP_208077265.1
• Coordinates: 2859126..2859386 (+)
• Length: 87 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: J3359_RS12890
• Protein ID: WP_208077264.1
• Coordinates: 2858878..2859126 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J3359_RS12860 (J3359_12860)	2855346..2855588	+	243	WP_208077258.1	hypothetical protein	-
J3359_RS12865 (J3359_12865)	2855588..2855986	+	399	WP_208077259.1	type II toxin-antitoxin system VapC family toxin	-
J3359_RS12870 (J3359_12870)	2856107..2856382	-	276	WP_208077260.1	hypothetical protein	-
J3359_RS12875 (J3359_12875)	2856447..2856914	+	468	WP_208077261.1	DUF1569 domain-containing protein	-
J3359_RS12880 (J3359_12880)	2856943..2858373	+	1431	WP_208077262.1	DASS family sodium-coupled anion symporter	-
J3359_RS12885 (J3359_12885)	2858448..2858813	+	366	WP_208077263.1	S24 family peptidase	-
J3359_RS12890 (J3359_12890)	2858878..2859126	+	249	WP_208077264.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
J3359_RS12895 (J3359_12895)	2859126..2859386	+	261	WP_208077265.1	Txe/YoeB family addiction module toxin	Toxin
J3359_RS12900 (J3359_12900)	2859405..2860679	+	1275	WP_208077266.1	Y-family DNA polymerase	-
J3359_RS12905 (J3359_12905)	2860892..2861323	-	432	WP_208077267.1	exosortase F system-associated protein	-
J3359_RS12910 (J3359_12910)	2861320..2861856	-	537	WP_208077268.1	exosortase family protein XrtF	-
J3359_RS12915 (J3359_12915)	2861908..2862360	+	453	WP_208077269.1	GAF domain-containing protein	-
J3359_RS12920 (J3359_12920)	2862406..2863392	+	987	WP_208077270.1	lytic polysaccharide monooxygenase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-84)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-71)

Sequences

Toxin

Protein

• Length: 87 a.a.
• Molecular weight: 10472.17 Da
• Isoelectric Point: 9.6572

>T197084 WP_208077265.1 NZ_CP071869:2859126-2859386 [Polaribacter cellanae]
MQLIWSTKSWNDYLYWQKVDKKIAKRINELLKVCMRTPFEGIGKPEALKNNLQGYWSRRITSEHRLVYKCENEELFILAC
RYHYGQ

Nucleotide

• Length: 261 bp

>T197084 NZ_CP095540:1971434-1971841 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATTCCCTGGCCGCTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGCATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCGCCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGACAGCGGAAAACGGCA
ACATTTATGGCTGGCAGCTGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATATTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9428.76 Da
• Isoelectric Point: 4.8483

>AT197084 WP_208077264.1 NZ_CP071869:2858878-2859126 [Polaribacter cellanae]
MEIVNYTDFRSNLKHWFEKVINDVSDVVIKRKNGKDLVLISLDEYNSLKETNYLLSGKNGAVLLDSIEELESGKGLRKEL
IE

Nucleotide

• Length: 249 bp

>AT197084 NZ_CP095540:1971187-1971453 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCACCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCAGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA