Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | yafN-yafO (relBE)/YafO-YafN |
| Location | 1230204..1230907 | Replicon | chromosome |
| Accession | NZ_CP071848 | ||
| Organism | Vibrio sp. SCSIO 43136 | ||
Toxin (Protein)
| Gene name | yafO | Uniprot ID | - |
| Locus tag | J4N39_RS05795 | Protein ID | WP_252023001.1 |
| Coordinates | 1230204..1230617 (-) | Length | 138 a.a. |
Antitoxin (Protein)
| Gene name | yafN | Uniprot ID | - |
| Locus tag | J4N39_RS05800 | Protein ID | WP_252023003.1 |
| Coordinates | 1230614..1230907 (-) | Length | 98 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| J4N39_RS05780 (J4N39_05780) | 1225724..1226647 | + | 924 | WP_252022995.1 | 23S rRNA pseudouridine(2605) synthase RluB | - |
| J4N39_RS05785 (J4N39_05785) | 1226887..1228026 | + | 1140 | WP_252022996.1 | SIR2 family protein | - |
| J4N39_RS05790 (J4N39_05790) | 1228023..1229831 | + | 1809 | WP_252022999.1 | ATP-binding protein | - |
| J4N39_RS05795 (J4N39_05795) | 1230204..1230617 | - | 414 | WP_252023001.1 | type II toxin-antitoxin system YafO family toxin | Toxin |
| J4N39_RS05800 (J4N39_05800) | 1230614..1230907 | - | 294 | WP_252023003.1 | hypothetical protein | Antitoxin |
| J4N39_RS05805 (J4N39_05805) | 1231205..1231630 | - | 426 | WP_252023005.1 | hypothetical protein | - |
| J4N39_RS05810 (J4N39_05810) | 1231698..1232093 | - | 396 | WP_252023008.1 | hypothetical protein | - |
| J4N39_RS05815 (J4N39_05815) | 1232308..1232763 | - | 456 | WP_252023010.1 | hypothetical protein | - |
| J4N39_RS05820 (J4N39_05820) | 1232833..1233153 | - | 321 | WP_252023012.1 | HI1450 family dsDNA-mimic protein | - |
| J4N39_RS05825 (J4N39_05825) | 1233156..1233722 | - | 567 | WP_252023014.1 | elongation factor P-like protein YeiP | - |
| J4N39_RS05830 (J4N39_05830) | 1234237..1235034 | + | 798 | WP_252023016.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 138 a.a. Molecular weight: 15924.18 Da Isoelectric Point: 6.9118
>T197039 WP_252023001.1 NZ_CP071848:c1230617-1230204 [Vibrio sp. SCSIO 43136]
VKDKPLKVRIFKHKILIEALSENELEALISDFKTYKETGQKPDTFGRDEAYDHPNTLPILKSEEVRHIHLAAHDAPFLSA
VQFYQTSDKHLVYCQGWEDPKCYLLIAILAPDAHEQARNRNIMHNLGVIAERFRQQF
VKDKPLKVRIFKHKILIEALSENELEALISDFKTYKETGQKPDTFGRDEAYDHPNTLPILKSEEVRHIHLAAHDAPFLSA
VQFYQTSDKHLVYCQGWEDPKCYLLIAILAPDAHEQARNRNIMHNLGVIAERFRQQF
Download Length: 414 bp
>T197039 NZ_CP095533:c2412237-2412130 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGAATTATTACCGCAGCGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA
Antitoxin
Download Length: 98 a.a. Molecular weight: 10603.94 Da Isoelectric Point: 4.4678
>AT197039 WP_252023003.1 NZ_CP071848:c1230907-1230614 [Vibrio sp. SCSIO 43136]
MKTSTIYAEKAVSSSEARKHFKDCLSGEPVVVLSNNEPAGYMMSADFFEGLMKALEDKNPNSVASFRPMTARLDAIAQLN
AKALADLDENDIGNFQE
MKTSTIYAEKAVSSSEARKHFKDCLSGEPVVVLSNNEPAGYMMSADFFEGLMKALEDKNPNSVASFRPMTARLDAIAQLN
AKALADLDENDIGNFQE
Download Length: 294 bp
>AT197039 NZ_CP095533:2412290-2412351 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|