Detailed information of TA system TA196932

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-YefM
• Location: 2339820..2340331
• Replicon: chromosome
• Accession: NZ_CP071794
• Organism: Parasphingorhabdus cellanae strain JHSY0214

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: J4G78_RS11210
• Protein ID: WP_207986652.1
• Coordinates: 2340065..2340331 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: J4G78_RS11205
• Protein ID: WP_243457063.1
• Coordinates: 2339820..2340068 (+)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
J4G78_RS11185 (J4G78_11185)	2334926..2335516	+	591	WP_207986647.1	methionine biosynthesis protein MetW	-
J4G78_RS11190 (J4G78_11190)	2335522..2337471	-	1950	WP_207986648.1	prolyl oligopeptidase family serine peptidase	-
J4G78_RS11195 (J4G78_11195)	2337661..2337819	-	159	WP_207986649.1	hypothetical protein	-
J4G78_RS11200 (J4G78_11200)	2337983..2339776	+	1794	WP_207986650.1	SLC13 family permease	-
J4G78_RS11205 (J4G78_11205)	2339820..2340068	+	249	WP_243457063.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
J4G78_RS11210 (J4G78_11210)	2340065..2340331	+	267	WP_207986652.1	Txe/YoeB family addiction module toxin	Toxin
J4G78_RS11215 (J4G78_11215)	2340586..2342154	-	1569	WP_207986653.1	peptide chain release factor 3	-
J4G78_RS11220 (J4G78_11220)	2342156..2344630	-	2475	WP_207986654.1	phenylalanine--tRNA ligase subunit beta	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (5-88)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (3-71)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10671.24 Da
• Isoelectric Point: 10.3364

>T196932 WP_207986652.1 NZ_CP071794:2340065-2340331 [Parasphingorhabdus cellanae]
MKLAFSEKAWNHYLYWQDKDRKTLKRINALLEECRRHPFEGTGKPEPLRGQLKGWWSRRITQEHRLVYRVRGEGGAQVLE
VAQCRYHY

Nucleotide

• Length: 267 bp

>T196932 NZ_CP095514:c3063290-3063036 [Escherichia coli]
GTGAAACTAATCTGGTCTGAGGAATCATGGGATGATTATCTGTACTGGCAGGAAACAGATAAGCGAATTGTTAAAAAGAT
CAATGAAATTATCAAAGATACACGCAGAACACCATTTGAAGGTAAGGGGAAGCCAGAACCCCTGAAACATAATTTGTCAG
GCTTCTGGTCCCGACGCATTACAGAGGAGCACCGTCTGGTATACGCGGTTACCGACGATTCACTGCTCATTGCAGCATGT
CGTTATCATTATTGA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9033.24 Da
• Isoelectric Point: 4.3690

>AT196932 WP_243457063.1 NZ_CP071794:2339820-2340068 [Parasphingorhabdus cellanae]
MENFSNARANLKALMDRVVADRAPVKITRQRGEAVVMIAESEWAGMEETIHLLSSPANAKELLESIAQLDAGEGQERELI
DP

Nucleotide

• Length: 249 bp

>AT196932 NZ_CP095514:c3063538-3063287 [Escherichia coli]
ATGCGTACAATTAGCTACAGCGAAGCGCGTCAGAATTTGTCGGCAACAATGATGAAAGCCGTTGAAGATCATGCCCCGAT
CCTCATTACTCGTCAGAATGGAGAGGCTTGTGTTCTGATGTCACTCGAAGAATACAACTCGCTGGAAGAGACGGCTTATC
TACTGCGTTCCCCCGCTAACGCCCGGAGATTGATGGACTCAATCGATAGCCTGAAATCAGGCAAAGGAACGGAAAAGGAC
ATTATTGAGTGA