Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 2231068..2231587 Replicon chromosome
Accession NZ_CP071697
Organism Streptococcus suis strain 1112S

Toxin (Protein)


Gene name yoeB Uniprot ID A0A116LVN8
Locus tag J1N58_RS10590 Protein ID WP_029176515.1
Coordinates 2231068..2231325 (-) Length 86 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A0M9FLP3
Locus tag J1N58_RS10595 Protein ID WP_029693536.1
Coordinates 2231327..2231587 (-) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-75)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 10290.79 Da        Isoelectric Point: 8.0279

>T196737 WP_029176515.1 NZ_CP071697:c2231325-2231068 [Streptococcus suis]
MGIHFTEDAWEDYLYWQSQDKKTLKRINKIIKDMQRHPFEGIAKPEPLKYDYQGAWSRRIDAENRLIYMVEANRLCILSL
KDHYG

Download         Length: 258 bp

>T196737 NZ_CP095276:c2992845-2992492 [Enterobacter hormaechei subsp. xiangfangensis]
GTGTGGGCGATTAAAACTACGGACAGGTTTGACGACTGGTTCACCTCATTAAACGATAGCGAGAGAGCCAGCGTACTGGC
CGCGCTACTTGTTTTGCGGGAGAGGGGACCGGGTCTGTCCAGACCGTATGCCGATACGCTGAAAGGCTCCCGCCACAGCA
ACATGAAAGAGTTGCGTATCCAGAGTAAGGGTGATCCGCTGAGGGCATTTTTCGCTTTCGATCCGAACCGTACGGGTATT
GTACTGTGTGCGGGCAATAAGGTCGGTAATGAAAGGCGATTTTACGATGAGATGCTCCTCGTTGCGGATCGGGAATACAC
TCGCTGGCTGAACACATTAAAAGAGAGGAATTAA

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9950.29 Da        Isoelectric Point: 5.1255

>AT196737 WP_029693536.1 NZ_CP071697:c2231587-2231327 [Streptococcus suis]
MEAIVYSHFRNHLKDYMKKVNDEFEPLVVVNKNPEEDIVVLSKSEWDSLQETLAVARNTYLSQKVLRGMAQVKAGQTQER
NLIEAD

Download         Length: 261 bp

>AT196737 NZ_CP095276:c2992487-2992185 [Enterobacter hormaechei subsp. xiangfangensis]
ATGGGCAGAACCCTGGAGCAGCTTATTGCAGATGAAAAACCTGAGGTTGTTGCCAGCGCACAGGCAATGGCAACGGATAT
TTTGCTCAATATCCATCTGGCCGAGTTACGTGAAAAAGTGCAAAAAACGCAGGTAGATATGGCCAGGGCGTTGGGTATTA
AACAACCTACTGTCGCCGTCATGGAAAAGGCAGGACGCGATATTAAGCTTTCTTCTTTGAAACGCTTCGTTGAGGCCGCC
GGAGGGAAGCTACGGCTGGATGTAGAACTACCCGATGGTTCTCATTACGAGTTTGTGTTGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A116LVN8

Antitoxin

Source ID Structure
AlphaFold DB A0A0M9FLP3

References