Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 1176498..1177018 Replicon chromosome
Accession NZ_CP071684
Organism Bifidobacterium longum subsp. longum strain JCM 11342

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag BLL342_RS04920 Protein ID WP_117701510.1
Coordinates 1176498..1176752 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag BLL342_RS04925 Protein ID WP_117701509.1
Coordinates 1176752..1177018 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
BLL342_RS04895 1172130..1173806 - 1677 WP_100969855.1 ATP-binding protein -
BLL342_RS04900 1173895..1174140 - 246 WP_007053507.1 hypothetical protein -
BLL342_RS04905 1174379..1174927 + 549 WP_193027347.1 hypothetical protein -
BLL342_RS04910 1174938..1175205 + 268 Protein_944 hypothetical protein -
BLL342_RS04915 1175405..1176394 + 990 WP_193027345.1 hypothetical protein -
BLL342_RS04920 1176498..1176752 - 255 WP_117701510.1 Txe/YoeB family addiction module toxin Toxin
BLL342_RS04925 1176752..1177018 - 267 WP_117701509.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
BLL342_RS04930 1177187..1177567 + 381 WP_193027343.1 hypothetical protein -
BLL342_RS04935 1177590..1177955 + 366 WP_193027342.1 hypothetical protein -
BLL342_RS04940 1178332..1179186 - 855 WP_193027419.1 hypothetical protein -
BLL342_RS04945 1179454..1179771 - 318 WP_131207568.1 HigA family addiction module antidote protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1122795..1179771 56976


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(3-75)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9863.31 Da        Isoelectric Point: 8.2604

>T196649 WP_117701510.1 NZ_CP071684:c1176752-1176498 [Bifidobacterium longum subsp. longum]
MLLCWTDDAWADYLYWQSQDRKTLKRINALIRDMQRTPFEGIGKPEPLRCGLSGAWSRRIDSANRIIYTVADDRLCILSA
KDHY

Download         Length: 255 bp

>T196649 NZ_CP095240:c4310937-4310719 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9911.09 Da        Isoelectric Point: 4.3417

>AT196649 WP_117701509.1 NZ_CP071684:c1177018-1176752 [Bifidobacterium longum subsp. longum]
MTQAVAYSNFRANLKTYMRRVNEDADTLLVTNADPEDNVVVMSADDYDSLMETLRVYQNPYLSDKVTRGMAQVRQGQTMA
RDLVEAGA

Download         Length: 267 bp

>AT196649 NZ_CP095240:c4311338-4310964 [Klebsiella pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References