Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 69942..70467 Replicon plasmid p2
Accession NZ_CP071620
Organism Rhizobium bangladeshense strain PLR8-1a

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag J2J97_RS23895 Protein ID WP_207609240.1
Coordinates 70195..70467 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag J2J97_RS23890 Protein ID WP_064707332.1
Coordinates 69942..70193 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
J2J97_RS23880 66457..67800 - 1344 WP_138396155.1 adenylate/guanylate cyclase domain-containing protein -
J2J97_RS23885 68492..69829 + 1338 WP_064713262.1 nucleotide sugar dehydrogenase -
J2J97_RS23890 69942..70193 + 252 WP_064707332.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
J2J97_RS23895 70195..70467 + 273 WP_207609240.1 Txe/YoeB family addiction module toxin Toxin
J2J97_RS23900 70500..71672 - 1173 WP_207609241.1 DUF3095 family protein -
J2J97_RS23905 71797..72276 + 480 WP_138396149.1 class I SAM-dependent methyltransferase -
J2J97_RS23910 72373..72873 + 501 WP_207609242.1 GFA family protein -
J2J97_RS23915 72894..73349 - 456 WP_064707328.1 Rrf2 family transcriptional regulator -
J2J97_RS23920 73483..74388 + 906 WP_207603683.1 FAD-dependent oxidoreductase -
J2J97_RS23925 74554..74994 + 441 WP_064707326.1 DUF805 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..458357 458357


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-72)


Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10730.37 Da        Isoelectric Point: 9.4680

>T196616 WP_207609240.1 NZ_CP071620:70195-70467 [Rhizobium bangladeshense]
MKLLWTPNSWEEYEYWQKTDQKLVEKISELLRDTKRSPFKGLGKPEPLKGDLSGFWSRRILGEHRLVYCVTGKGASQQLE
IIQCRFHYEK

Download         Length: 273 bp

>T196616 NZ_CP095180:c4206059-4205718 [Enterobacter roggenkampii]
ATGAAAACTTTACCTGCAACAACTCAGCGGGCGGTGAAGCCCTGCCTGTCACCCGTGGCTGTCTGGCAAATGCTACTGAC
CCGCCTGCTGAAACAGCACTATGGTCTCACCCTCAACGACACACCGTTCAGTGAGGAACGTGTTATACAGGAACATATCG
ATGCCGGAATCACGCTGGCTGATGCCGTGAATTTTCTGGTGGAAAAATACGAACTGGTGCGTATCGACAGGAAGGGATTT
AACTGGCAGGAACAATCACCTTATCTTCGGGCAGCAGATATTCTGCGAGCACGGCAGGCAACTGGCTTGTTGCGGCAAAG
CCGTAACAACGTAGTACGGTGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9289.53 Da        Isoelectric Point: 5.6513

>AT196616 WP_064707332.1 NZ_CP071620:69942-70193 [Rhizobium bangladeshense]
MAHVRLTEFRQNIATYFDQVLSSRAPLLVTRQGSEAMVLIAESEYESMQETLHLLSTPANSARLRESIGQLRSGQGIEKD
PTL

Download         Length: 252 bp

>AT196616 NZ_CP095180:c4206397-4206080 [Enterobacter roggenkampii]
ATGAGCAACATTACATGGGGGCTGCAGCGGGCTATCACGCCACGCCTGGGAGCCCGTCTGGTGCAGGAGGGGAACCGGCT
GCATTATCTGGCTGACCGGGCCAGCATCACCGGTAAATTCAGTGACGTCGAATGCCGTAAGCTGGATGAAACATTCCCGC
ACTTTATCAGCCAGATGGAGTCGATGCTGACCACCGATGAACTGAATCCCCGCCATGCCCACTGCGTCACCCTGTACCAC
AACGGTTTCACCTGCGAAGCTGATACTCTTGGCAGTTGCGGCTACGTATACATCGCCATTTACCCCACTCAGAGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References